hemoglobin

Examples of hemoglobin in the following topics:

• Homologs, Orthologs, and Paralogs

  • For example, the hemoglobin gene of humans and the myoglobin gene of chimpanzees are paralogs.
  • The genes encoding myoglobin and hemoglobin are considered to be ancient paralogs.
  • Similarly, the four known classes of hemoglobins (hemoglobin A, hemoglobin A2, hemoglobin B, and hemoglobin F) are paralogs of each other.
  • While each of these proteins serves the same basic function of oxygen transport, they have already diverged slightly in function: fetal hemoglobin (hemoglobin F) has a higher affinity for oxygen than adult hemoglobin.

• Anaerobiosis and N2 Fixation

  • It has close chemical and structural similarities to hemoglobin, and, like hemoglobin, is red in colour.
  • Leghemoglobin has a high affinity for oxygen, about ten times higher than of human hemoglobin.

• Biosynthesis of Tetrapyrroles

  • Heme is a cofactor of the protein hemoglobin.
  • Hemoglobin and myoglobin are two O2-binding proteins that contain iron porphyrins.

• The Iron Cycle

  • Animals acquire iron when they consume plants, and iron is utilized by vertebrates in hemoglobin, the oxygen-binding protein found in red blood cells.

• Malaria

  • The symptoms that persist due to parasitic infection are a result of the release of merozoites into the bloodstream, destruction of the red blood cells and the free circulation of large amounts of hemoglobin in the red blood cells due to disruption.

• Siderophores

  • Iron is tightly bound to proteins such as hemoglobin, transferrin, lactoferrin, and ferritin.

• Primary Immunodeficiency Diseases

  • Hgb=Hemoglobin, WBC=White blood cells, Plt=Platelets, Hct=Hematocrit.