the simplex method
(noun)
An algorithm that optimizes a system of linear inequalities.
Examples of the simplex method in the following topics:
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Application of Systems of Inequalities: Linear Programming
- The most common method in linear programming is the Simplex Method, or the Simplex Algorithm.
- To use the Simplex Method, we need to represent the problem using linear equations.
- In the second step, Phase II, the Simplex Algorithm is applied using the solution found in Phase I as a starting point.
- Now, the Simplex Method proceeds by performing successive pivot operations which each improve the basic feasible solution; the choice of pivot element at each step is largely determined by the requirement that this pivot improves the solution.
- Use the Simplex Method to solve applications of systems of linear inequalities
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Infection
- Infections of the integumentary system include athlete's foot and herpes simplex.
- Herpes simplex is most easily transmitted by direct contact with a lesion or the body fluid of an infected individual.
- Barrier protection methods are the most reliable method of preventing transmission of herpes, but they merely reduce rather than eliminate risk.
- Condom use reduces the transmission risk of herpes simplex significantly.
- Differentiate between the integumentary system infections of athlete's foot and herpes simplex
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Introduction to kinds of graphs
- The social relations being described here are also simplex (in figures 3.2 and 3.3).
- Figure 3.4 is an example of one method of representing multiplex relational data with a single graph.
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Double-Stranded DNA Viruses: Herpesviruses
- In this fashion, the virus can persist in the cell (and thus the host) indefinitely.
- There is no method to eradicate the herpes virus from the body, but antiviral medications, such as acyclovir, can reduce the frequency, duration, and severity of outbreaks.
- Various viruses from the Herpesviridae family seen using an electron micrograph Amongst these members is varicella-zoster (Chickenpox), and herpes simplex type 1 and 2 (HSV-1, HSV-2).
- This negatively-stained transmission electron micrograph (TEM) revealed the presence of numerous herpes simplex virions, members of the Herpesviridae family.
- There are two strains of the herpes simplex virus, HSV-1, which is responsible for cold sores, and HSV-2, which is responsible for genital herpes.
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Attachment and Entry of Herpes Simplex
- Herpes simplex virus attaches to a host's cells with viral envelope glycoproteins, which then allows entry of the viral capsid into the host cell.
- Herpes simplex viruses 1 and 2 (HSV-1 and HSV-2) are two members of the herpes virus family, Herpesviridae, that infect humans.
- The receptor provides a strong, fixed attachment to the host cell.
- Herpes simplex virus attaches to host cell surface receptors using glycoproteins.
- Following attachment, the viral envelope fuses with the host cell membrane and the viral capsid gains entry into the cell.
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Viral Skin Diseases
- Herpes simplex is a viral disease from the herpesviridae family caused by both Herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2).
- Herpes simplex is most easily transmitted by direct contact with a lesion or the body fluid of an infected individual.
- Barrier protection methods are the most reliable method of preventing transmission of herpes, but they merely reduce rather than eliminate risk.
- Once infected, the virus remains in the body for life.
- The pain and rash most commonly occurs on the torso, but can appear on the face, eyes, or other parts of the body.
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Replication of Herpes Simplex Virus
- The viral genome immediately travels to the nucleus but the VHS protein remains in the cytoplasm.
- The late proteins form the capsid and the receptors on the surface of the virus.
- Packaging of the viral particles — including the genome, core and the capsid - occurs in the nucleus of the cell.
- Entry of HSV into the host cell involves interactions of several glycoproteins on the surface of the enveloped virus, with receptors on the surface of the host cell.
- Structure of the conserved core of the herpes simplex virus transcriptional regulatory protein VP16.
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Simplex or multiplex relations in the graph
- In our simple example, we showed two graphs of simple (sometimes referred to as "simplex" to differentiate from "multiplex") relations.
- The friendship graph (figure 3.2) showed a single relation (that happened to be binary and directed).
- The spouse graph (figure 3.3) showed a single relation (that happened to be binary and un-directed).
- ).We also combined the information about multiple ties into a single line.
- Alternatively, one might use different symbols, colors, line widths, or other devices to keep all of the information about multiple relations visible in a multiplex graph -- but the result can often be too complicated to be useful.
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Animal Viruses
- When a protein in the viral capsid binds to its receptor on the host cell, the virus may be taken inside the cell via a vesicle during the normal cell process of receptor-mediated endocytosis.
- An alternative method of cell penetration used by non-enveloped viruses is for capsid proteins to undergo shape changes after binding to the receptor, creating channels in the host cell membrane.
- Other viruses cause long-term chronic infections, such as the virus causing hepatitis C, whereas others, like herpes simplex virus, cause only intermittent symptoms.
- As mentioned, herpes simplex virus can remain in a state of latency in nervous tissue for months, even years.
- Under certain conditions, including various types of physical and psychological stress, the latent herpes simplex virus may be reactivated and undergo a lytic replication cycle in the skin, causing the lesions associated with the disease.
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Other Infectious Eye Diseases
- Fungi and viruses such as herpes simplex can cause eye infections.
- Herpetic simplex keratitis is a form of keratitis caused by recurrent herpes simplex virus in cornea.
- Herpes simplex virus (HSV) infection is very common in humans.
- The following classification of herpes simplex keratitis is important for understanding this disease:
- Summarize the various types of herpes simplex keratitis: dendritic ulcer (epithelial keratitis) and disciform keratitis (stromal keratitis)