Treponema pallidum

(noun)

A Gram-negative spirochaete bacterium with subspecies that cause treponemal diseases such as syphilis, bejel, pinta, and yaws.

Related Terms

Examples of Treponema pallidum in the following topics:

  • Syphilis

    • Syphilis is a sexually transmitted infection (STI) caused by the bacterium Treponema pallidum.
    • Syphilis is a sexually transmitted infection (STI) caused by the spirochete bacterium Treponema pallidum .
    • The brain and spinal cord become infected with the syphilis bacterium, Treponema pallidum, during the secondary stage of infection and can remain latent for 10 to 20 years after the initial infection.
    • This electron micrograph shows Treponema pallidum on cultures of cotton-tail rabbit epithelium cells (Sf1Ep).

  • Syphilis

    • Syphilis is a sexually transmitted infection caused by the spirochete bacterium Treponema pallidum subspecies pallidum.
    • Syphilis is a sexually transmitted infection caused by the spirochete bacterium Treponema pallidum subspecies pallidum .
    • Other human diseases caused by related Treponema pallidum include yaws (subspecies pertenue), pinta (subspecies carateum) and bejel (subspecies endemicum).
    • This electron micrograph shows Treponema pallidum on cultures of cotton-tail rabbit epithelium cells (Sf1Ep).

  • Blood-Brain Barrier

    • An exception to the bacterial exclusion are the diseases caused by spirochetes, such as Borrelia, which causes Lyme disease, and Treponema pallidum, which causes syphilis.
    • Exceptions to the bacterial exclusion are the diseases caused by spirochetes, such as Borrelia (the cause of Lyme disease), and Treponema pallidum, which causes syphilis.

  • Microbial Evasion of Phagocytosis

    • Treponema pallidum, the bacterium that causes syphilis, hides from phagocytes by coating its surface with fibronectin, which is produced naturally by the body and plays a crucial role in wound healing.

  • Basal Ganglia

    • the globus pallidus, or pallidum (composed of globus pallidus externa (GPe) and globus pallidus interna (GPi)).
    • The pallidum receives its most important input from the striatum (either directly or indirectly), and sends inhibitory output to a number of motor-related areas, including the part of the thalamus that projects to the motor-related areas of the cortex.
    • One part of substantia nigra, the reticulata (SNr), functions similarly to the pallidum, and another part (compacta or SNc) provides the source of the neurotransmitter dopamine's input to the striatum.
    • The subthalamic nucleus (STN) receives input mainly from the striatum and cortex, and projects to a portion of the pallidum (interna portion or GPi).

  • The Role of the Basal Ganglia in Movement

    • The role in motivation of the "limbic" part of the basal ganglia (the nucleus accumbens (NA), ventral pallidum, and ventral tegmental area VTA)is particularly well established.
    • The inputs from the cortex and thalamus to the striatum and subthalamic nucleus are glutamatergic, but the outputs from the striatum, pallidum, and substantia nigra pars reticulata all use GABA.