Examples of syphilis in the following topics:
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- Late latent syphilis is asymptomatic, and not as contagious as early latent syphilis.
- Patient with tertiary (gummatous) syphilis.
- People with tertiary syphilis are not infectious.
- Gummatous syphilis or late benign syphilis usually occurs one to 46 years after the initial infection, with an average of 15 years.
- It is the causative agent of syphilis.
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- Syphilis is a sexually transmitted infection (STI) caused by the bacterium Treponema pallidum.
- Latent syphilis displays little to no symptoms, and neurosyphilis (tertiary) can result in neurological and cardiac symptoms because the syphilis has been undiagnosed or untreated for many years.
- Neurosyphilis occurs when syphilis is left untreated from many years.
- Dermatologic manifestations are the hallmark of secondary syphilis.
- It is the causative agent of syphilis.
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- Among the most common are Herpes simplex virus (HSV), the genital herpes agent ; Treponema pallidum, that causes syphilis; Chlamydia trachomatis, the cause of chlamydia; and Haemophilus ducreyi, the chancroid agent.
- In the United States, the most common reasons for genital ulcers in young and sexually active patients are genital herpes and syphilis.
- In the U.S., testing is recommended for syphilis (by serology and darkfield microscopy) and HSV (culture, serology or PCR), and in cases of chancroid outbreaks or based on the medical history, for the presence of Haemophilus ducreyi.
- Syphilis, genital herpes and chancroid have all been associated with increasing the risk for HIV transmission.
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- Several studies that, when brought to light, led to the introduction of ethical principles guiding human subjects research and Institutional Review Boards to ensure compliance with those principles, are worth noting, including the Tuskegee syphilis experiment, in which 399 impoverished black men with syphilis were left untreated to track the progress of the disease and Nazi experimentation on humans.
- Reverby found that such unethical experiments were more widespread than just the widely known Tuskegee study and that the US Government funded a study in which thousands of Guatemalan prisoners were infected with syphilis to determine whether they could be cured with penicillin.
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- Public Health Service sought to study the natural progression of untreated syphilis in poor, rural black men who thought they were receiving free health care from the U.S. government.
- Out of the 600 men involved in the experiment, 399 had previously contracted syphilis before the study; they were never told they had syphilis, however, and were led to believe they were receiving free general medical care.
- One of the most unethical aspects of the experiment was that by 1947, penicillin was widely recognized as the standard treatment for syphilis.
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- Globally, untreated maternal syphilis still causes more than 650,000 adverse pregnancy outcomes, including about 350,000 pre-birth deaths, each year.
- The overwhelming majority of these are in countries with limited laboratory capacity for syphilis testing as part of basic pregnancy care.
- Congenital syphilis, passed from mother to child, can be eliminated through universal screening of pregnant women early in pregnancy, and prompt treatment with at least one injection of penicillin.
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- This test is useful for bacteria such as syphilis spirochete, which are not readily cultivated in a laboratory, or if a rapid diagnosis is essential for the survival of a patient.
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- Tests for the identification of Treponema pallidium (causes syphilis) and HSV (Herpes Simplex Virus, type 2) may be performed to exclude the possibility that ulcers are caused by those agents instead of Haemophilus ducreyi.
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- An exception to the bacterial exclusion are the diseases caused by spirochetes, such as Borrelia, which causes Lyme disease, and Treponema pallidum, which causes syphilis.
- Exceptions to the bacterial exclusion are the diseases
caused by spirochetes, such as Borrelia (the cause of Lyme disease), and
Treponema pallidum, which causes syphilis.