Examples of macrophage in the following topics:
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- The main types of phagocytes are monocytes, macrophages, neutrophils, tissue dendritic cells, and mast cells.
- Mature macrophages are derived from monocytes, granulocyte stem cells, or the cell division of pre-existing macrophages.
- Macrophages do not have granules, but contain many lysosomes.
- Macrophages cause inflammation through the production of interleukin-1, interleukin-6, and TNF-alpha.
- Neutrophils die after phagocytosis, becoming pus that is later cleaned up by macrophages.
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- They can activate macrophages and natural killer (NK) cells to attack and lyse virus-infected cells.
- One common interferon is IFN-gamma, a pyrogen involved in inflammatory response and macrophage and NK cell activation.
- This category also includes cytokines that are only involved in leukocyte migration, such as CCL2 which causes monocyte chemotaxis and stimulates its differentiation into macrophages inside of tissues.
- It is a protein released by NK cells, macrophages, and helper T cells, typically in systemic immune responses.
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- The different types of white blood cells (leukocytes) include neutrophils, basophils, eosinophils, lymphocytes, monocytes, and macrophages.
- Monocytes are large leukocytes that differentiate into macrophages and dendritic cells under varying conditions, while performing similar functions in phagocytosis and antigen presentation (the process by which molecular components are presented to lymphocytes to stimulate an adaptive immune response).
- Macrophages are monocytes that have migrated out of the blood stream and into the internal body tissues.
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- The epithelial cells and macrophages of the lungs secrete many molecules that have immune system functions.
- Immunoglobin A (IgA): An antibody that can attack pathogens and mark them for phagocytosis from macrophages and neutrophils.
- Protease: Secreted from lung macrophages and neutrophils during inflammatory response to damage pathogens.
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- Lymph nodes are repositories of B cells, T cells, and other immune system cells, such as dendritic cells and macrophages.
- The medulla contains plasma cells, macrophages, and B cells as well as sinuses, which are vessel-like spaces that the lymph flows into.
- Macrophages in the sinus spaces phagocytize (engulf) foreign particles such as pathogen, so that lymph fluid that returns to the bloodstream is cleaned of problematic abnormalities.
- This fluid may carry a higher amount of debris, so inflammation occurs as more neutrophils and later macrophages enter the node to remove debris from the lymph.
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- This process is performed primarily by neutrophils, macrophages, and dendritic cells, but most other leukocytes can do it as well.
- This process is primarily performed by macrophages and dendritic cells.
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- Virtually all nucleated cells, but especially endo/epithelial cells and resident macrophages (many near the interface with the external environment) are potent producers of IL-1, IL-6, and TNF-α.
- These cytokines induce the chemotaxis to the site of infection in its target cells (e.g., neutrophils, dendritic cells and macrophages).
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- The protoplatelets then break up into hundreds of platelets that circulate throughout the bloodstream, while the remaining nucleus of the ruptured megakaryocyte is consumed by macrophages.
- Old platelets are destroyed by macrophage phagocytosis in the spleen and by Kupffer cells in the liver.
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- Helper T cells secrete cytokines such as interferon-gamma, which can activate cytotoxic T cells and macrophages.
- This diagram of adaptive immunity indicates the flow from antigen to APC, MHC2, CD4+, T helper cells, B cells, antibodies, macrophages, and killer T cells.
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- Macrophages phagocytose (ingest) the fibers and stimulate fibroblasts to deposit connective tissue.
- Due to the asbestos fibers' natural resistance to digestion, the macrophage dies off, releasing cytokines and attracting further lung macrophages and fibrolastic cells to lay down fibrous tissue which eventually forms a fibrous mass.