cleavage

Examples of cleavage in the following topics:

• Cleavage of the Zygote

  • The different cells derived from cleavage up to the blastula stage are called blastomeres.
  • Holoblastic cleavage occurs in animals with little yolk in their eggs.
  • Since cleavage is impeded by the vegetal pole, there is a very uneven distribution and size of cells.
  • In holoblastic eggs, the first cleavage always occurs along the vegetal–animal axis of the egg, and the second cleavage is perpendicular to the first.
  • From here, the spatial arrangement of blastomeres can follow various patterns, due to different planes of cleavage in various organisms.The end of cleavage is known as the midblastula transition and coincides with the onset of zygotic transcription.

• Lines of Cleavage and Surgery

  • Cleavage lines are topological lines drawn on a map of the human body and correspond to the orientation of collagen fibers in the dermis.
  • Langer's lines, sometimes called cleavage lines, are topological lines drawn on a map of the human body .

• Gastrulation

  • Gastrulation takes place after cleavage and the formation of the blastula and the primitive streak.

• Tissue Development

  • During the next stage, termed cleavage, mitotic cell divisions transform the zygote into a tiny ball of cells, called a blastula.

• Coagulation

  • Plasmin: generated by proteolytic cleavage of plasminogen, a potent fibrinolytic that degrades fibrin and destroys clots.

• Role of the Complement System in Immunity

  • When stimulated by one of several triggers, proteases in the system cleave specific proteins to release cytokines and initiate an amplifying cascade of further cleavages.