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Repression of Anabolic Pathways
Annotated Crystal Structure of Dimeric LacI
Annotated crystal structure of dimeric LacI. Two monomers (of four total) cooperate to bind each DNA operator sequence. Monomers (red and blue) contain DNA binding and core domains (labeled) which are connected by a linker (labeled). The C-terminal tetramerization helix is not shown. The repressor is shown in complex with operator DNA (gold) and ONPF (green), an anti-inducer ligand (i.e. a stabilizer of DNA binding).
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"LacI Dimer Structure Annotated."
http://en.wikipedia.org/wiki/File:LacI_Dimer_Structure_Annotated.png
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