BSE infected brain tissue
This micrograph of brain tissue reveals the cytoarchitectural histopathologic changes found in bovine spongiform encephalopathy. The presence of vacuoles, i.e. microscopic "holes" in the gray matter, gives the brain of BSE-affected cows a sponge-like appearance when tissue sections are examined in the lab.
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"Aphis.usda.gov BSE 5."
http://commons.wikimedia.org/wiki/File:Aphis.usda.gov_BSE_5.jpg
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