Examples of micro-organism in the following topics:
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Antibiotic Discovery
- Observations of antibiosis between micro-organisms led to the discovery of natural antibacterials produced by microorganisms.
- More recent observations made in the laboratory of antibiosis between micro-organisms led to the discovery of natural antibacterials produced by microorganisms.
- After screening hundreds of dyes against various organisms, he discovered a medicinally useful drug, the synthetic antibacterial Salvarsan now called arsphenamine.
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Control of Nosocomial Infections
- Two categories of micro-organisms can be present on health care workers' hands: transient flora and resident flora.
- The first is represented by the micro-organisms taken by workers from the environment, and the bacteria in it.
- The second group is represented by the permanent micro-organisms living on the skin surface, on the stratum corneum or immediately under it.
- They are worn to reduce the likelihood the hands of personnel contaminated with micro-organisms from a patient or a fomite (contaminated object) can be transmitted to another patient.
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Syntrophy
- A cow eats a lot of grass, the cellulose of which is transformed into lipids by micro-organisms in the cow's large intestine.
- Yet another example is the community of micro-organisms in soil that live off leaf litter.
- Such relationships are called reciprocal syntrophy because the plant lives off the products of micro-organisms.
- These organisms are facultative anaerobes.
- These reduced organic compounds are generally small organic acids and alcohols derived from pyruvate, the end product of glycolysis.
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Effects of Drug Combinations
- This is due to the phenomenon of resistance, whereby a micro-organism gains the ability to resist an antimicrobial drug, while initially the drug effectively slowed the growth of or even killed the target micro-organism.
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Bacterial Polyesters
- To produce PHA, a culture of a micro-organism such as Alcaligenes eutrophus is placed in a suitable medium and fed appropriate nutrients so that it multiplies rapidly.
- Another even larger scale synthesis can be done with the help of soil organisms.
- Once the population has reached a substantial level, the nutrient composition is changed to force the micro-organism to synthesize PHA.
- There are also applications for PHA produced by micro-organisms within the medical and pharmaceutical industries, primarily due to their biodegradability.
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Iron Oxidation
- Ferric iron (Fe3+) is a widespread anaerobic terminal electron acceptor both for autotrophic and heterotrophic organisms.
- Electron flow in these organisms is similar to those in electron transport, ending in oxygen or nitrate, except that in ferric iron-reducing organisms the final enzyme in this system is a ferric iron reductase.
- Model organisms include Shewanella putrefaciens and Geobacter metallireducens.
- G. metallireducens) can use toxic hydrocarbons such as toluene as a carbon source, there is significant interest in using these organisms as bioremediation agents in ferric iron-rich contaminated aquifers .
- These micro-organisms (for example Gallionella ferruginea or Leptothrix ochracea) live at the oxic-anoxic interfaces and are microaerophiles.
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Limitation of Microbial Growth by Nutrient Supply
- The nutrients used to propagate growth are organism-specific, based on their cellular and metabolic processes. .
- Essential nutrients are nutrients absolutely required by an organism.
- Two categories of essential nutrients are macro- and micro-nutrients.
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Sources of Essential Nutrients
- Micro-nutrients help enzyme function and maintain protein structure.
- Organisms usually absorb carbon when it is in its organic form.
- Carbon in its organic form is usually a product of living things.
- It is essential to the metabolism of many organisms.
- Without sufficient phosphate, an organism will cease to grow.
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RNA Regulation and Antisense RNA
- Gene regulation, the ability to control whether a gene is expressed or not, is critical in controlling cellular and metabolic processes and contributes to diversity and variation in organisms.
- There are specific types of RNA molecules that can be utilized to control gene regulation, including messenger RNAs (mRNAs), small RNAs such as microRNAs and lastly, antisense RNAs.
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Carboxysomes
- They are proteinaceous structures resembling phage heads in their morphology; they contain the enzymes of carbon dioxide fixation in these organisms.
- Carboxysomes are an example of a wider group of protein micro-compartments that have dissimilar functions but similar structures, based on homology of the two shell protein families.