notochord
Physiology
(noun)
A structure found in the embryos of vertebrates from which the spine develops.
Biology
Examples of notochord in the following topics:
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Characteristics of Chordata
- Animals in the phylum Chordata share four key features: a notochord, a dorsal hollow nerve cord, pharyngeal slits, and a post-anal tail.
- In some chordates, the notochord acts as the primary axial support of the body throughout the animal's lifetime.
- The notochord, however, is replaced by the vertebral column (spine) in most adult vertebrates.
- In chordates, it is located dorsally (at the top of the animal) to the notochord.
- In chordates, four common features appear at some point during development: a notochord, a dorsal hollow nerve cord, pharyngeal slits, and a post-anal tail.
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Phylum Chordata
- The phylum Chordata contains all animals that have a dorsal notochord at some stage of development; in most cases, this is the backbone.
- A notochord, or a longitudinal, flexible rod between the digestive tube and the nerve cord .
- A dorsal nerve cord which develops from a plate of ectoderm that rolls into a tube located dorsal to the notochord.
- For example, tunicate larvae have both a notochord and a nerve cord which are lost in adulthood .
- All chordates possess a notochord, or a type of flexible support rod, at some point in their development.
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Chordates and the Evolution of Vertebrates
- Adults only maintain pharyngeal slits and lack a notochord, a dorsal hollow nerve cord, and a post-anal tail.
- Members of Cephalochordata possess a notochord, dorsal hollow nerve cord, pharyngeal slits, and a post-anal tail in the adult stage.
- They do not have a true brain, but the notochord extends into the head, which gives the subphylum its name ( "cephalo" is Greek for head).
- (c) In the adult stage, the notochord, nerve cord, and tail disappear.
- Adult lancelets retain the four key features of chordates: a notochord, a dorsal hollow nerve cord, pharyngeal slits, and a post-anal tail.
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Bilaminar Embryonic Disc Development
- As gastrulation progresses, the embryonic disc becomes trilaminar and the notochord is formed.
- Through the through the process of neurulation, the notochord induces the formation of the notochord in the embryonic disc.
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Neurulation
- Following gastrulation, the neurulation process develops the neural tube in the ectoderm, above the notochord of the mesoderm.
- After gastrulation, the notochord—a flexible, rod-shaped body that runs along the back of the embryo—is formed from the mesoderm.
- During the third week of gestation the notochord sends signals to the overlying ectoderm, inducing it to become neuroectoderm.
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Agnathans: Jawless Fishes
- The skeleton of a hagfish is composed of cartilage, which includes a cartilaginous notochord that runs the length of the body.
- This notochord provides support to the hagfish's body.
- Unlike true vertebrates, hagfishes do not replace the notochord with a vertebral column during development.
- Their notochord is surrounded by a cartilaginous structure called an arcualia, which may resemble an evolutionarily-early form of the vertebral column.
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Characteristics of Vertebrates
- However, the subphylum Vertebrata is distinguished from the phylum Chordata by the development of the notochord into a bony backbone.
- In vertebrates, the notochord develops into the vertebral column or spine: a series of bony vertebrae each separated by mobile discs .
- However, a few vertebrates have secondarily lost their vertebrae and, instead, retain the notochord into adulthood (e.g., the sturgeon fish).
- In chordates, the central nervous system is based on a hollow nerve tube that runs dorsal to the notochord along the length of the animal.
- All chordates are deuterostomes, possessing a notochord.
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Vertebrate Axis Formation
- They found that the transplanted embryo now had two notochords: one at the dorsal site from the original cells and another at the transplanted site.
- This suggested that the dorsal cells were genetically programmed to form the notochord and define the dorsal-ventral axis.
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Establishing Body Axes during Development
- They found that the transplanted embryo now had two notochords: one at the dorsal site from the original cells and another at the transplanted site.
- This suggested that the dorsal cells were genetically programmed to form the notochord and define the axis.
- These cell types are specified by the secretion of Shh from the notochord (located ventrally to the neural tube), and later from the floor plate cells.
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The Evolution of Craniata and Vertebrata
- In adult vertebrates, the vertebral column replaces the embryonic notochord.