hemangioblast
(noun)
A primitive mesodermal cell that is the precursor of endothelial cells and of blood.
Examples of hemangioblast in the following topics:
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Development of Blood and Blood Vessels
- The former requires differentiation of endothelial cells from hemangioblasts and then organization into a primary capillary network.
- This led to the hypothesis that the two lineages come from the same precursor, termed hemangioblast.
- Even though there is evidence that corroborates a hemangioblast, the isolation and exact location in the embryo has been difficult to pinpoint.
- Then in 1932, Murray detected the same event and coined the term hemangioblast.
- Further evidence to corroborate hemangioblasts comes from the expression of various genes such as CD34 and Tie2 by both lineages.
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Development of Blood
- Blood islands form in the yolk sac of an embryo by cellular differentiation of hemangioblasts into endothelial cells.