6.1 The Mole

Figure 6.1 "Water Molecules" shows that we need 2 hydrogen atoms and 1 oxygen atom to make 1 water molecule. If we want to make 2 water molecules, we will need 4 hydrogen atoms and 2 oxygen atoms. If we want to make 5 molecules of water, we need 10 hydrogen atoms and 5 oxygen atoms. The ratio of atoms we will need to make any number of water molecules is the same: 2 hydrogen atoms to 1 oxygen atom.

One problem we have, however, is that it is extremely difficult, if not impossible, to organize atoms one at a time. As stated in the introduction, we deal with billions of atoms at a time. How can we keep track of so many atoms (and molecules) at a time? We do it by using mass rather than by counting individual atoms.

A hydrogen atom has a mass of approximately 1 u. An oxygen atom has a mass of approximately 16 u. The ratio of the mass of an oxygen atom to the mass of a hydrogen atom is therefore approximately 16:1.

If we have 2 atoms of each element, the ratio of their masses is approximately 32:2, which reduces to 16:1—the same ratio. If we have 12 atoms of each element, the ratio of their total masses is approximately (12 × 16):(12 × 1), or 192:12, which also reduces to 16:1. If we have 100 atoms of each element, the ratio of the masses is approximately 1,600:100, which again reduces to 16:1. As long as we have equal numbers of hydrogen and oxygen atoms, the ratio of the masses will always be 16:1.

The same consistency is seen when ratios of the masses of other elements are compared. For example, the ratio of the masses of silicon atoms to equal numbers of hydrogen atoms is always approximately 28:1, while the ratio of the masses of calcium atoms to equal numbers of lithium atoms is approximately 40:7.

So we have established that the masses of atoms are constant with respect to each other, as long as we have the same number of each type of atom. Consider a more macroscopic example. If a sample contains 40 g of Ca, this sample has the same number of atoms as there are in a sample of 7 g of Li. What we need, then, is a number that represents a convenient quantity of atoms so we can relate macroscopic quantities of substances. Clearly even 12 atoms are too few because atoms themselves are so small. We need a number that represents billions and billions of atoms.

Chemists use the term moleA number of things equal to 6.022 × 10²³ items. to represent a large number of atoms or molecules. Just as a dozen implies 12 things, a mole (mol) represents 6.022 × 10²³ things. The number 6.022 × 10²³, called Avogadro’s numberThe value 6.022 × 10²³. after the 19th-century chemist Amedeo Avogadro, is the number we use in chemistry to represent macroscopic amounts of atoms and molecules. Thus, if we have 6.022 × 10²³ O atoms, we say we have 1 mol of O atoms. If we have 2 mol of Na atoms, we have 2 × (6.022 × 10²³) Na atoms, or 1.2044 × 10²⁴ Na atoms. Similarly, if we have 0.5 mol of benzene (C₆H₆) molecules, we have 0.5 × (6.022 × 10²³) C₆H₆ molecules, or 3.011 × 10²³ C₆H₆ molecules.

Notice that we are applying the mole unit to different types of chemical entities. In these examples, we cited moles of atoms and moles of molecules. The word mole represents a number of things—6.022 × 10²³ of them—but does not by itself specify what “they” are. They can be atoms, formula units (of ionic compounds), or molecules. That information still needs to be specified.

Because 1 H₂ molecule contains 2 H atoms, 1 mol of H₂ molecules (6.022 × 10²³ molecules) has 2 mol of H atoms. Using formulas to indicate how many atoms of each element we have in a substance, we can relate the number of moles of molecules to the number of moles of atoms. For example, in 1 mol of ethanol (C₂H₆O), we can construct the following relationships (Table 6.1 "Molecular Relationships"):

The following example illustrates how we can use these relationships as conversion factors.

The fact that 1 mol equals 6.022 × 10²³ items can also be used as a conversion factor.