Phineas Gage's skull
The case of Phineas Gage was one of the first indicators of a biological basis for personality.
Source
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"870-frontispiece-623x1024.jpe."
http://en.wikipedia.org/wiki/File:JacksonJBS_A_descriptive_catalogue_of_the_Warren_Anatomical_Museum_1870_frontispiece_623x1024.jpg
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