Concept
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Agonists, Antagonists, and Drugs
![Nicotinic acetylcholine receptors](../../../../../../../../../figures.boundless-cdn.com/24496/full/nicotinic-receptors.jpg)
Nicotinic acetylcholine receptors
NAchR are cholinergic receptors that form ligand-gated ion channels in the plasma membranes of certain neurons and on the postsynaptic side of the neuromuscular junction.Â
This is a diagram of two nicotinic acetylcholine receptors—one is homomeric and the other is heteromeric. Both are ligand-gated ion channels with binding sites for acetylcholine as well as other agonists. When agonists bind to a receptor it stabilizes the open state of the ion channel allowing an influx of cations.
Source
Boundless vets and curates high-quality, openly licensed content from around the Internet. This particular resource used the following sources:
"Drug Discovery and Development: Nicotinic Acetylcholine Receptor Agonists."
http://en.wikipedia.org/wiki/Drug_Discovery_and_Development:_Nicotinic_Acetylcholine_Receptor_Agonists
Wikipedia
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