mannan-binding-lectin

Examples of mannan-binding-lectin in the following topics:

• Role of the Complement System in Immunity

  • The antibody binds to an antigen on the surface of a pathogen, activating the C1 complement protein.
  • The lectin pathway is not caused by antibody binding, but by a carbohydrate-binding-protein called mannan-binding-lectin (MBL).
  • It is an acute phase reactant produced in the liver and binds to the carbohydrates on the surfaces of many pathogens.
  • The steps for the lectin pathway are:

• Coryza and Influenza

  • HA is a lectin that mediates binding of the virus to target cells and entry of the viral genome into the target cell, while NA is involved in the release of progeny virus from infected cells, by cleaving sugars that bind the mature viral particles.