Examples of lipase in the following topics:
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- Pancreatic lipase breaks down triglycerides into free fatty acids and monoglycerides.
- Pancreatic lipase works with the help of the salts from bile secreted by the liver and the gall bladder.
- Bile salts attach to triglycerides, helping emulsify them, which aids access by pancreatic lipase; the lipase is water-soluble, but the fatty triglycerides are hydrophobic, tending to orient toward each other and away from the watery intestinal surroundings.
- The bile salts act as the "main man" that holds the triglycerides in the watery surroundings until the lipase can break them into the smaller components that are able to enter the villi for absorption.
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- Fats are digested by lipases which hydrolyze the glycerol-fatty acid bonds.
- Lipases are found in the mouth, the stomach, and the pancreas.
- However, it can continue to operate on food stored in the fundus of the stomach, and as much as 30% of the fats can be digested by this lipase.
- Gastric lipase is of little importance in humans.
- Pancreatic lipase accounts for the majority of fat digestion and operates in conjuction with the bile salts.
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- Pancreatic lipase breaks down triglycerides into free fatty acids and monoglycerides.
- Pancreatic lipase works with the help of the salts from the bile secreted by the liver and the gall bladder.
- Bile salts attach to triglycerides to help emulsify them, which aids access by pancreatic lipase.
- This occurs because the lipase is water-soluble, but the fatty triglycerides are hydrophobic and tend to orient towards each other and away from the watery intestinal surroundings.
- The bile salts are the "main man" that holds the triglycerides in the watery surroundings until the lipase can break them into the smaller components that are able to enter the villi for absorption.
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- Digestion of certain fats begins in the mouth, where lingual lipase breaks down short chain lipids into diglycerides.
- The presence of fat in the small intestine produces hormones that stimulate the release of pancreatic lipase from the pancreas, and bile from the liver, enabling the breakdown of fats into fatty acids.
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- Pancreatic juice is a liquid secreted by the pancreas, which contains a variety of enzymes including trypsinogen, chymotrypsinogen, elastase, carboxypeptidase, pancreatic lipase, nucleases, and amylase.
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- This main product of fat digestion is first broken down to fatty acids and glycerol through hydrolysis using lipoprotein lipase.
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- These enzymes include peptidases, sucrase, maltase, lactase and intestinal lipase.
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- The vesicle then fuses with a lysosome, which has an enzyme called lysosomal acid lipase that hydrolyzes the cholesterol esters.
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- The cells are filled with secretory granules containing the inactivated digestive enzymes, mainly trypsinogen, chymotrypsinogen, pancreatic lipase, and amylase, that are secreted into the lumen of the acini.
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- These include salivary amylase, which aids in the chemical breakdown of polysaccharides such as starch into disaccharides such as maltose; and lingual lipase, which hydrolyzes long-chain triglycerides into partial glycerides and free fatty acids.