Examples of goblet cell in the following topics:
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- While both the small intestine and the large intestine have goblet cells that secrete mucin to form mucus in water, they are abundant in the large intestine.
- The crypts and intestinal villi are covered by epithelium that contains two types of cells: goblet cells that secrete mucus and enterocytes that secrete water and electrolytes.
- This is in contrast to the stomach, where the chief cells secrete pepsinogen.
- During each mitosis, one of the two daughter cells remains in the crypt as a stem cell, while the other differentiates and migrates up the side of the crypt and eventually into the villus.
- Goblet cells are among the cells produced in this fashion.
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- Substances are transported through the endothelial cells themselves within vesicles.
- The substance to be transported is endocytosed by the endothelial cell into a lipid vesicle which moves through the cell and is then exocytosed to the other side.
- Listeria monocytogenes has been shown to enter the intestinal lumen via transcytosis across goblet cells.
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- The submucosal glands are a companion to unicellular goblet cells, which also produce mucus, and are found lining the same tubes.
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- The mucosa, composed of simple epithelium cells, is the innermost layer of the gastrointestinal (GI) tract.
- It is composed of epithelium cells and a thin connective tissue.
- The mucosa contains specialized goblet cells that secrete sticky mucus throughout the GI tract.
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- Different types of cells are at different locations down the pits.
- The cells at the base of these pits are chief cells that are responsible for the production of pepsinogen, an inactive precursor of pepsin, which degrades proteins.
- The secretion of pepsinogen prevents self-digestion of the stomach cells.
- Further up the pits, parietal cells produce gastric acid and a vital substance, intrinsic factor.
- Near the top of the pits, closest to the contents of the stomach, there are mucus-producing cells called goblet cells that help protect the stomach from self-digestion.
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- It is lined with pseudostratified ciliated columnar epithelium cells with goblet cells that produce mucus.
- This mucus and cilia of the trachea form the mucociliary escalator,
which lines the cells of the trachea with mucus to trap inhaled foreign
particles.
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- While both the small intestine and the large intestine have goblet cells, they are more abundant in the large intestine.
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- The hormone gastrin causes an increase in the secretion of HCl from the parietal cells and pepsinogen from the chief cells in the stomach.
- Gastrin is released by G-cells in the stomach, via the base cells of the pyloric, cardiac, and fundic glands, in response to distension of the antrum, and digestive products (especially large quantities of incompletely digested proteins).
- Parietal cells secrete hydrochloric acid and intrinsic factor
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- Obstruction of the lumen of the bronchiole by mucoid exudate, goblet cell metaplasia, epithelial basement membrane thickening, and severe inflammation of bronchiole.
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- T helper cells assist the maturation of B cells and memory B cells while activating cytotoxic T cells and macrophages.
- Differentiation into helper T cell subtypes occurs during clonal selection following T cell activation of naive T cells.
- Cytotoxic T cells (TC cells, or CTLs) destroy virus-infected cells and tumor cells, and cause much of the damage in in transplant rejection and autoimmune diseases.
- Memory T cells comprise two subtypes: central memory T cells (TCM cells) and effector memory T cells (TEM cells), which have different properties and release different cytokines.
- Regulatory T cells (Treg cells), also known as suppressor T cells, are crucial for the maintenance of immunological tolerance.
