Examples of goblet cells in the following topics:
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- While both the small intestine and the large intestine have goblet cells that secrete mucin to form mucus in water, they are abundant in the large intestine.
- The crypts and intestinal villi are covered by epithelium that contains two types of cells: goblet cells that secrete mucus and enterocytes that secrete water and electrolytes.
- This is in contrast to the stomach, where the chief cells secrete pepsinogen.
- During each mitosis, one of the two daughter cells remains in the crypt as a stem cell, while the other differentiates and migrates up the side of the crypt and eventually into the villus.
- Goblet cells are among the cells produced in this fashion.
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- The types of epithelia are classified by the shapes of cells present and the number of layers of cells.
- The cell outline is slightly irregular; cells fit together to form a covering or lining.
- Goblet cells are interspersed in some tissues (such as the lining of the trachea).
- The goblet cells contain mucous that traps irritants, which, in the case of the trachea, keep these irritants from getting into the lungs.
- Goblet cells secret mucous into the digestive tract lumen.
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- Substances are transported through the endothelial cells themselves within vesicles.
- The substance to be transported is endocytosed by the endothelial cell into a lipid vesicle which moves through the cell and is then exocytosed to the other side.
- Listeria monocytogenes has been shown to enter the intestinal lumen via transcytosis across goblet cells.
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- The submucosal glands are a companion to unicellular goblet cells, which also produce mucus, and are found lining the same tubes.
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- The mucosa, composed of simple epithelium cells, is the innermost layer of the gastrointestinal (GI) tract.
- It is composed of epithelium cells and a thin connective tissue.
- The mucosa contains specialized goblet cells that secrete sticky mucus throughout the GI tract.
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- A biofilm is an aggregate of microorganisms in which cells adhere to each other on a surface.
- These adherent cells are frequently embedded within a self-produced matrix of extracellular polymeric substance (EPS).
- The patients with biofilms were shown to have been denuded of cilia and goblet cells, unlike the controls without biofilms who had normal cilia and goblet cell morphology.
- In addition, it has been demonstrated that the gonococcus can form biofilms on glass surfaces and over human cells.
- There is evidence for the formation of gonococcal biofilms on human cervical epithelial cells during natural disease.
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- Different types of cells are at different locations down the pits.
- The cells at the base of these pits are chief cells that are responsible for the production of pepsinogen, an inactive precursor of pepsin, which degrades proteins.
- The secretion of pepsinogen prevents self-digestion of the stomach cells.
- Further up the pits, parietal cells produce gastric acid and a vital substance, intrinsic factor.
- Near the top of the pits, closest to the contents of the stomach, there are mucus-producing cells called goblet cells that help protect the stomach from self-digestion.
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- It is lined with pseudostratified ciliated columnar epithelium cells with goblet cells that produce mucus.
- This mucus and cilia of the trachea form the mucociliary escalator,
which lines the cells of the trachea with mucus to trap inhaled foreign
particles.
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- While both the small intestine and the large intestine have goblet cells, they are more abundant in the large intestine.
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- The hormone gastrin causes an increase in the secretion of HCl from the parietal cells and pepsinogen from the chief cells in the stomach.
- Gastrin is released by G-cells in the stomach, via the base cells of the pyloric, cardiac, and fundic glands, in response to distension of the antrum, and digestive products (especially large quantities of incompletely digested proteins).
- Parietal cells secrete hydrochloric acid and intrinsic factor