buffy coat

(noun)

The fraction of an anticoagulated blood sample that contains most of the white blood cells and platelets following density gradient centrifugation of the blood.

Related Terms

Examples of buffy coat in the following topics:

  • Transfusions of Whole Blood

    • Platelets for transfusion can also be prepared from the buffy coat of whole blood, which has therapeutic benefits for those with platelet disorders or impaired clotting ability.
    • Centrifuge quickly separates whole blood into plasma, buffy coat, and red cells by using centrifugal force to drop the cellular components to the bottom of a container.

  • Gross Anatomy of the Stomach

    • They supply the muscular coat, ramify in the submucous coat, and are finally distributed to the mucous membrane.
    • Nerve plexuses are found in the submucous coat and between the layers of the muscular coat as in the intestine.

  • Microbial Evasion of Phagocytosis

    • Treponema pallidum, the bacterium that causes syphilis, hides from phagocytes by coating its surface with fibronectin, which is produced naturally by the body and plays a crucial role in wound healing.
    • Bacteria often produce proteins or sugars that coat their cells and interfere with phagocytosis; these are called capsules.

  • Orbits

    • The primary functions of the orbit include protection of its delicate contents and, through muscle attachment and a smooth coating fascia, to  also promote the smooth, delicate movements of the eye.

  • Development of Joints

    • Histological image of the hyaline cartilage which coats the articular surfaces of joints.

  • Absorption and Feces Formation in the Large Intestine

  • Physiology of Lactation

    • It contains higher amounts of white blood cells and antibodies than mature milk, and is especially high in immunoglobulin A (IgA), which coats the lining of the baby's immature intestines, and helps to prevent pathogens from invading the baby's system.

  • Regulation of Blood Cholesterol Levels

    • Upon binding of apolipoprotein B100, many LDL receptors become localized in clathrin-coated pits.

  • Antigens and Antigen Receptors

    • This includes parts (coats, capsules, cell walls, flagella, fimbrae, and toxins) of bacteria, viruses, and other microorganisms.

  • Tissue Development

    • Filled with uterine fluid, the blastocyst breaks out of the egg coating and undergoes implantation.