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Mutation
![The distribution of fitness effects](../../../../../../../../../figures.boundless-cdn.com/13184/full/800px-dfe-in-vsv.jpg)
The distribution of fitness effects
The distribution of fitness effects of mutations in vesicular stomatitis virus. In this experiment, random mutations were introduced into the virus by site-directed mutagenesis. The fitness of each mutant was compared with the ancestral type. A fitness of zero, less than one, one, more than one, respectively, indicates that mutations are lethal, deleterious, neutral, and advantageous.
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