Examples of indel in the following topics:
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- Comparative analyses of the sequenced genomes have also led to discovery of many conserved indels in widely distributed proteins and whole proteins (i.e. signature proteins) that are distinctive characteristics of either all Alphaproteobacteria, or their different main orders (viz.
- Phylogenetic analyses and conserved indels in large numbers of other proteins provide evidence that Alphaproteobacteria have branched off later than most other phyla and Classes of Bacteria with the exception of Betaproteobacteria and Gammaproteobacteria.
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- The species from this group can be distinguished from all other bacteria by the presence of conserved indels in a number of proteins such as RNA polymerase alpha subunit, Gyrase B, Elongation factor-Tu and Elongation factor-P, and by large numbers of signature proteins that are uniquely present in different chlamydiae species.
- Phylogeny and shared presence of conserved indels in proteins such as RNA polymerase Beta subunit and lysyl-tRNA synthetase indicate that Verrucomicrobia are the closest free-living relatives of these parasitic organisms.
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- Comparative genomic studies have identified six conserved signature indels (CSIs) that are specific for the species from the phylum Aquificae and provide potential molecular markers for it.
- However, a close relationship of the Aquificae to Thermotogae, and the deep branching of Aquificae, is not supported by phylogenetic studies based upon other gene/protein sequences and also by conserved signature indels in several highly-conserved universal proteins.
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- Comparative genomic studies have identified six conserved signature indels (CSIs) that are specific for the species from the phylum Aquificae and provide potential molecular markers for this phylum.
- However, a close relationship of the Aquificae to Thermotogae and the deep branching of Aquificae is not supported by phylogenetic studies based upon other gene/protein sequences and also by conserved signature indels in several highly conserved universal proteins.
- However, a recent comparative genomic study has identified large numbers of conserved signature indels (CSIs) in important proteins that are specific for either all Thermotogae species or a number of its sub-groups.
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- Archaea and Gram-positive bacteria also share conserved indels in a number of important proteins, such as Hsp70 and glutamine synthetase I.
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- No conserved signature indels were identified that were uniquely shared by the entire phylum.
- However, the classes "Chloroflexi" and Thermomicrobia were found to group together consistently by both phylogenetic means and the identification of shared conserved signature indels in the 50S ribosomal protein L19 and the enzyme UDP-glucose 4-epimerase.