immunocompromised
(adjective)
Having an immune system that has been impaired by disease or treatment.
Examples of immunocompromised in the following topics:
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Cytomegalovirus Infections
- Cytomegalovirus (CMV) is a type of herpesvirus that largely affects infants and the immunocompromised.
- Major areas of risk of infection include prenatal or postnatal infants and immunocompromised individuals, such as organ transplant recipients, persons with leukemia, or those infected with human immunodeficiency virus (HIV).
- HCMV infection is typically unnoticed in healthy people, but can be life-threatening for the immunocompromised, such as HIV-infected persons, organ transplant recipients, or newborn infants.
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Fungi
- Candida species are commonly known to cause opportunist infections in immunocompromised hosts.
- Candida species are commonly known to cause opportunist infections in immunocompromised hosts .
- The immunocompromised hosts that commonly become infected with Candida include transplant patients, cancer patients and AIDS sufferers.
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Vaccine Safety
- Immunocompromised individuals have generally been discouraged from receiving live-virus vaccines.
- These include current smallpox vaccines that cannot safely be given to immunocompromised people; the tuberculosis vaccine, which is not recommended for HIV-positive infants; and the yellow-fever vaccine, which puts elderly people at particular risk of a yellow-fever-like illness.
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Cryptococcosis
- Cryptococcus gattii causes infections in immunocompetent people (those having a functioning immune system), but C. neoformans v. grubii, and v. neoformans usually only cause clinically evident infections in persons who have some form of defect in their immune systems (immunocompromised persons).
- Although the most common presentation of cryptococcosis is of C. neoformans infection in an immunocompromised person (such as persons living with AIDS), the C. gattii is being increasingly recognised as a pathogen in presumptively immunocompetent hosts, especially in Canada and Australia.
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Listeriosis
- Listeriosis has a low incidence in humans and occurs in pregnant women, newborn infants, elderly patients, and patients who are immunocompromised.
- Another preventative measure is to advise high-risk groups such as pregnant women and immunocompromised patients to avoid unpasteurized pâtés and foods such as soft cheeses.
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Secondary Immunodeficiency Diseases
- A person who has an immunodeficiency of any kind is said to be immunocompromised.
- An immunocompromised person may be particularly vulnerable to opportunistic infections, in addition to normal infections that could affect everyone.
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Blastomycosis
- Amphotericin B is considerably more toxic, and is usually reserved for immunocompromised patients who are critically ill and those with central nervous system disease.
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Legionellosis
- Individuals particularly at risk are older individuals, those immunocompromised or with chronic lung disease.
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Cryptosporidiosis
- However, cryptosporidiosis is prevalent in immunocompromised individuals, such as those infected with the HIV virus.
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Cystitis
- However, under immunocompromised circumstances, i.e., weakened immunity, these bacteria can be found the culprit responsible for urinary tract infections such as cystitis and pyelonephritis.