acyclovir

Examples of acyclovir in the following topics:

• Antiviral DNA Synthesis Inhibitors

  • One of the most often used antiviral drugs that works with the described mechanism is acyclovir (aciclovir), a guanosine analogue.
  • However, both drugs are more toxic and have more serious side effects than acyclovir.
  • This drug is used in cases of resistance against acyclovir and ganciclovir nucleoside analogue chemicals.
  • Acyclovir does not contain a sugar molecule with a 3'-OH group and will interrupt the synthesis of a newly synthesized nucleotide chain if added to it.
  • The guanosine depicted in this specific image is used for RNA synthesis but acyclovir inhibits the synthesis of DNA synthesis.

• Genital Herpes

  • Among these drugs are: acyclovir, valacyclovir and famciclovir.Acyclovir is an antiviral drug used against herpes viruses, varicella-zoster, and Epstein-Barr Viruses.
  • Once in the body, it becomes the anti-herpes medicine, acyclovir.
  • It only comes in caplets and its advantage is that it has a longer duration of action than acyclovir.
  • Famciclovir is another antiviral drug that belongs to the same class of acyclovir and valacyclovir.
  • This drug has a longer duration of action than acyclovir and it only comes in tablets.

• Other Infectious Eye Diseases

  • Acyclovir ophthalmic ointment and Trifluridine eye drops have similar effectiveness but are more effective than Idoxuridine and Vidarabine eye drops.
  • Topical antiviral medications are not absorbed by the cornea through an intact epithelium, but orally administered acyclovir penetrates an intact cornea and anterior chamber.

• Viral Skin Diseases

  • Of these drugs, acyclovir has been the standard treatment.

• Double-Stranded DNA Viruses: Herpesviruses

  • There is no method to eradicate the herpes virus from the body, but antiviral medications, such as acyclovir, can reduce the frequency, duration, and severity of outbreaks.