spliceosome
(noun)
a dynamic complex of RNA and protein subunits that removes introns from precursor mRNA
Examples of spliceosome in the following topics:
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mRNA Processing
- The splicing of pre-mRNAs is conducted by complexes of proteins and RNA molecules called spliceosomes .
- Each spliceosome is composed of five subunits called snRNPs (for small nuclear ribonucleoparticles, and pronounced "snurps".)
- The snRNPs of the spliceosome were left out of this figure, but it shows the sites within the intron whose interactions are catalyzed by the spliceosome.
- The splicing process is catalyzed by large complexes called spliceosomes.
- Each spliceosome is composed of five subunits called snRNPs.
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RNA Splicing
- The splicing of messenger RNA is accomplished and catalyzed by a macro-molecule complex known as the spliceosome.
- The areas for ligation and cleavage are determined by the many sub-units of the spliceosome which include the branch site (A) and the 5' and 3' splice sites.
- Interactions between these sub-units and the small nuclear ribonucleoproteins (snRNP) found in the spliceosome create a spliceosome A complex which helps determine which introns to leave out and which exons to keep and bind together.