sialic

Examples of sialic in the following topics:

• Attachment and Entry to the Host Cell

  • HA proteins bind to cells with sialic acid on the membranes, such as cells in the upper respiratory tract or erythrocytes.
  • First, it allows the recognition of target vertebrate cells, accomplished through the binding of these cells' sialic acid-containing receptors.
  • HA binds to the monosaccharide sialic acid that is present on the surface of its target cells, which causes the viral particles to stick to the cell's surface.

• Replicative Cycle of Influenza A

  • Influenza viruses bind through hemagglutinin onto sialic acid sugars on the surfaces of epithelial cells, typically in the nose, throat, and lungs of mammals, and the intestines of birds (Step 1 in infection figure ).
  • As before, the viruses adhere to the cell through hemagglutinin; the mature viruses detach once their neuraminidase has cleaved sialic acid residues from the host cell.

• Antiviral Agents that Prevent Virus Uncoating or Release

  • It cleaves sialic acid from glycoproteins on the surface of the host cell and allows the viral particles to leave the cell.