mediated

(adjective)

Acting or brought about through an intervening agency.

Related Terms

Examples of mediated in the following topics:

  • Type IV (Delayed Cell-Mediated) Reactions

    • Type IV hypersensitivity reactions are cell-mediated and take 2 to 3 days to develop.
    • Therefore in cell mediated immunity cytokines are not always present.
    • Cell-mediated immunity is directed primarily at microbes that survive in phagocytes and microbes that infect non-phagocytic cells.
    • Unlike the other types, it is not antibody mediated but rather is a type of cell-mediated response.
    • Describe Type IV cell-mediated reactions and explain why they take two to three days to develop

  • Summary - Computer Mediated Education

    • Research seems to support computer mediated communications as a valid educational tool.
    • Instructional technologists, educational psychologists, and educators have spent much time developing strategies to use computer mediated communication as a way to enrich and empower student learning.

  • Resolving Conflicts

    • Methods of dispute resolution include: litigation, arbitration, mediation, and conciliation.
    • Mediation is a way of resolving disputes between two or more parties with concrete effects.
    • Typically, a third party, the mediator, assists the parties to negotiate a settlement.
    • The mediator acts as a neutral third party and facilitates rather than directs the process.
    • In mediation, the mediator tries to guide the discussion in a way that optimizes parties' needs, takes feelings into account, and reframes representations.

  • Hypersensitivity

    • Mediators: IgE and IgG4.
    • Mediators: IgM or IgG (complement fixation).
    • Mediators: IgG (complement).
    • Associated disorders: Contact dermatitis, Mantoux test, Chronic transplant rejection, Multiple sclerosis, T-cells VAutoimmune disease receptor mediated, Graves' disease,Myasthenia Gravis.
    • Mediators: IgM or IgG (complement).

  • References

    • Voices of the mind: A sociocultural approach to mediated action.

  • Mechanisms of Resistance

    • An example of antimicrobial resistance mediated by anaerobic atmosphere is the shutdown of bacterial protein synthesis by aminoglycosides.
    • Resistance can be mediated by the environment or the microorganism itself .
    • Environmentally-mediated antimicrobial resistance is affected by the environment's chemical and physical properties such as pH, anaerobic conditions, cation concentrations (calcium, magnesium), and thymine-thymidine content (available metabolites and nutrients).
    • Microorganism-mediated antimicrobial resistance is due to genetically-encoded traits of the microorganism and can be divided into intrinsic or acquired.
    • Microorganism-mediated antimicrobial resistance is acquired by gene change or exchange such as genetic mutations, acquisition of genes from other organisms via gene transfer mechanisms, or a combination of mutational and gene transfer events.

  • Classes of T Cells

    • T cells play a central role in cell-mediated immune response through the use of the surface T cell receptor to recognize peptide antigens.
    • Cellular immunity is mediated by T lymphocytes, also called T cells.
    • Their major role is to shut down T cell-mediated immunity toward the end of an immune reaction.

  • Endocytosis

    • In receptor-mediated endocytosis, as in phagocytosis, clathrin is attached to the cytoplasmic side of the plasma membrane.
    • If uptake of a compound is dependent on receptor-mediated endocytosis and the process is ineffective, the material will not be removed from the tissue fluids or blood.
    • Some human diseases are caused by the failure of receptor-mediated endocytosis.
    • For example, the form of cholesterol termed low-density lipoprotein or LDL (also referred to as "bad" cholesterol) is removed from the blood by receptor-mediated endocytosis.
    • In receptor-mediated endocytosis, uptake of substances by the cell is targeted to a single type of substance that binds to the receptor on the external surface of the cell membrane.

  • Cell-Mediated Immunity

    • Cell-mediated immunity involves cytotoxic T cells recognizing infected cells and bringing about their destruction.
    • Just as the humoral immune response has B cells which mediate its response, the cellular immune response has T cells, which recognize infected cells and destroy them before the pathogen inside can replicate and spread to infect other cells.
    • Cytotoxic T cells mediate one arm of the cellular immune response
    • A summary of how the humoral and cell-mediated immune responses are activated appears in .
    • Depending on the cytokines released, this activates either the humoral or the cell-mediated immune response.

  • Inflammation

    • An inflammatory response can be caused by any of numerous inflammatory mediators released from innate immune system cells.
    • After an inflammatory mediator is released in the bloodstream, a period of transient vasoconstriction, lasting only a few seconds, occurs.
    • Then blood vessels expand to undergo vasodilation from the stimulus of the vasoactive inflammatory mediator, which increases blood flow to the area.
    • Other inflammatory mediators, such as TNF-alpha and IL-1, increase the expression of adhesion molecules on vascular endothelial cells.
    • When acute inflammation ends (typically by release of anti-inflammatory mediators such as IL-10 or an end to the release of inflammatory mediators) resolution will occur if the problem is alleviated.