Margaret Sanger

(noun)

Margaret Higgins Sanger (September 14, 1879 – September 6, 1966) was an American birth control activist, sex educator and nurse. She published a monthly newsletter providing contraception information titled, The Woman Rebel.

Related Terms

Examples of Margaret Sanger in the following topics:

  • Women's Rights after Suffrage

    • The National Woman’s Party worked for women’s rights in the 1920s, while Margaret Sanger became a prominent advocate for birth control.
    • At the same time, Margaret Sanger led a movement to promote reproductive rights and contraception for women in the form of a groundbreaking newsletter and the country’s first legal birth control clinic.
    • Prominent civil rights attorney Clarence Darrow offered to defend Sanger free of charge.
    • Nine days after its opening, Sanger was arrested for distributing contraceptives.
    • Margaret Sanger was a nurse and pioneering educator and birth control activist in the 1920s.

  • The New Feminism

    • One especially important movement of the time was the "birth-control movement," led in large part by Margaret Sanger.
    • Bennett, Emma Goldman, and Margaret Sanger.
    • Sanger coined the term "birth control," which first appeared in her newsletter.
    • Sanger's goal of challenging the law was fulfilled when she was indicted in August, 1914, but the prosecution focused their attention on articles Sanger had written on marriage, rather than contraception.
    • Refusing to walk, Sanger and a co-worker were dragged out of the clinic by police officers.

  • DNA Sequencing Based on Sanger Dideoxynucleotides

    • Sanger sequencing is based on the incorporation and detection of labeled ddNTPs as terminal nucleotides in DNA amplification.
    • Sanger sequencing, also known as chain-termination sequencing, refers to a method of DNA sequencing developed by Frederick Sanger in 1977.
    • This is an example of the output of a Sanger sequencing read using fluorescently labelled dye-terminators.
    • Different types of Sanger sequencing, all of which depend on the sequence being stopped by a terminating dideoxynucleotide (black bars).

  • DNA Sequencing Techniques

    • The Sanger method is also known as the dideoxy chain termination method.
    • A Sanger sequencing reaction is just a modified in vitro DNA replication reaction.
    • The ddNTPs are what distinguish a Sanger sequencing reaction from just a replication reaction.
    • Most of the time in a Sanger sequencing reaction, DNA Polymerase will add a proper dNTP to the growing strand it is synthesizing in vitro.
    • Sanger sequence can only produce several hundred nucleotides of sequence per reaction.

  • Substitution

    • Nitrogen nucleophiles will also react, as evidenced by the use of Sanger's reagent for the derivatization of amino acids.
    • The resulting N-2,4-dinitrophenyl derivatives are bright yellow crystalline compounds that facilitated analysis of peptides and proteins, a subject for which Frederick Sanger received one of his two Nobel Prizes in chemistry.
    • For more information on Sanger, visit the following link (http://www.chemistry.msu.edu/Portraits/PortraitsHH_Detail.asp?
    • HH_LName=Sanger).

  • Strategies Used in Sequencing Projects

    • The strategies used for sequencing genomes include the Sanger method, shotgun sequencing, pairwise end, and next-generation sequencing.
    • The basic sequencing technique used in all modern day sequencing projects is the chain termination method (also known as the dideoxy method), which was developed by Fred Sanger in the 1970s.
    • Frederick Sanger's dideoxy chain termination method uses dideoxynucleotides, in which the DNA fragment can be terminated at different points.
    • Compare the different strategies used for whole-genome sequencing:  Sanger method, shotgun sequencing, pairwise-end sequencing, and next-generation sequencing

  • Metagenomics

    • Recent studies use "shotgun" Sanger sequencing or massively parallel pyrosequencing to get largely unbiased samples of all genes from all the members of the sampled communities.
    • These techniques for sequencing DNA generate shorter fragments than Sanger sequencing; 454 pyrosequencing typically produces ~400 bp reads, Illumina and SOLiD produce 25-75 bp reads.
    • These read lengths are significantly shorter than the typical Sanger sequencing read length of ~750 bp.

  • Introduction

    • María del Puig Andrés, Jennifer Buoy, Margaret Daigle-Riley, and Mervine S.

  • Use of Whole-Genome Sequences of Model Organisms

    • This was accomplished by Fred Sanger using shotgun sequencing.

  • The Role of the Conclusion

    • The same 'vehicle' or theme, for example, an anecdote about Margaret Thatcher, is employed to conclude the speech as was used initially to introduce it.