Examples of Malignant tumor in the following topics:
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- It is also a fundamental step in the transition of tumors from a dormant state to a malignant one, leading to the use of angiogenesis inhibitors.
- A malignant tumor consists of a population of rapidly-dividing and growing cancer cells.
- Evidence now suggests the blood vessel in a given solid tumor may, in fact, be mosaic vessels, composed of endothelial cells and tumor cells.
- This mosaicity allows for substantial shedding of tumor cells into the vasculature, possibly contributing to the appearance of circulating tumor cells in the peripheral blood of patients with malignancies.
- As malignancy develops, cells progress from a prevascular stage (normal to early hyperplasia) to a vascular stage (late hyperplasia to dysplasia to invasive carcinoma).
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- The main idea is stimulating the patient's immune system to attack the malignant tumor cells that are responsible for the disease.
- GD2 is thus a convenient tumor-specific target for immunotherapies.
- In the case of cancer tumors, the microenvironment is immunosuppressive, allowing even those tumors that present unusual antigens to survive and flourish in spite of the immune response generated by the cancer patient against his own tumor tissue.
- Dermatologists use new creams and injections in the management of benign and malignant skin tumors.
- Injection immunotherapy uses mumps, candida, or trichophytin antigen injections to treat warts (HPV-induced tumors).
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- Cancer, known medically as a malignant neoplasm, is a broad group of various diseases, all involving unregulated cell growth.
- Cancers comprise the malignant (having a tendency to become worse) subset of neoplasms—a cell or group of cells that undergo unregulated growth and form a mass of tissue—often referred to as a tumor.
- Non-malignant tumors are referred to as benign; they are typically slower growing and are often surrounded by a membrane of connective tissue that prevents metatasis.
- A common example of a benign tumor is a skin mole.
- Malignant transformation can occur through the formation of novel oncogenes, the inappropriate over-expression of normal oncogenes, or by the under-expression or disabling of tumor suppressor genes.
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- Even for the relatively few cases in which malignant cancer has spread widely, modern chemotherapy offers a cure rate of at least 80%.
- Not all lumps on the testicles are tumors, and not all tumors are malignant; there are many other conditions such as testicular microlithiasis, epididymal cysts, appendix testis (hydatid of Morgagni), and so on which may be painful but are non-cancerous.
- Most of the remaining 5% are sex cord-gonadal stromal tumors derived from Leydig cells or Sertoli cells.
- low back pain (lumbago) tumor spread to the lymph nodes along the back
- About half of germ cell tumors of the testis are seminomas.
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- Cancer occurs after a single cell in a tissue is progressively genetically damaged to produce a cancer stem cell possessing a malignant phenotype.
- The newly formed "daughter" tumor in the adjacent site within the tissue is called a local metastasis.
- Malignant cells can break away from the primary tumor and attach to and degrade proteins that make up the surrounding extracellular matrix (ECM).
- The tumor cells are then transported to regional lymph nodes and ultimately, to other parts of the body.
- Transcoelomic: The spread of a malignancy into body cavities can occur via seeding the surface of the peritoneal, pleural, pericardial, or subarachnoid spaces.
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- Brain tumors include all tumors inside the cranium or in the central spinal canal.
- Brain tumors may also spread from cancers primarily located in other organs (metastatic tumors).
- Visibility of signs and symptoms of brain tumors mainly depends on two factors: tumor size (volume) and tumor location.
- The symptom onset—in the timeline of the development of the neoplasm—depends in many cases on the nature of the tumor but in many cases is also related to the change of the neoplasm from "benign" (i.e., slow-growing/late symptom onset) to more malignant (fast growing/early symptom onset).
- Radiotherapy: the most commonly used treatment for brain tumors, the tumor is targeted with alpha and beta rays to shrink the tumor
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- Spinal cord compression develops when the spinal cord is compressed by bone fragments from a vertebral fracture, a tumor, abscess, ruptured intervertebral disc, or other lesion .
- The most common causes of cord compression are tumors, but abscesses and granulomas (e.g. in tuberculosis) are equally capable of producing the syndrome.
- Emergency radiation therapy (usually 20 Gray in five fractions, 30 Gray in 10 fractions or eight Gray in one fraction) is the mainstay of treatment for malignant spinal cord compression.
- Some tumors are highly sensitive to chemotherapy (e.g. lymphomas, small-cell lung cancer) and may be treated with chemotherapy alone.
- The median survival of patients with metastatic spinal cord compression is about 12 weeks, reflecting the generally advanced nature of the underlying malignant disease.
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- DNA tumor viruses have two life-styles.
- The first DNA tumor viruses to be discovered were rabbit fibroma virus and Shope papilloma virus, both discovered by Richard Shope in the 1930s.
- They were discovered by making a filtered extract of a tumor from a wild rabbit and injecting the filtrate into another rabbit in which a benign papilloma grew.
- However, when the filtrate was injected into a domestic rabbit, the result was a carcinoma, a malignant growth.
- A seminal observation was that it was no longer possible to isolate infectious virus from the malignant growth because the virus had become integrated into the chromosomes of the malignant cells.
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- Viruses can cause cancer by transforming a normal cell into a malignant cell.
- Most viral infections, however, do not lead to tumor formation; several factors influence the progression from viral infection to cancer development.
- Scientists have been able to discern some commonality among viruses that cause tumors.
- The tumor viruses or oncoviruses change cells by integrating their genetic material with the host cell's DNA .
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- Skin cancers are abnormal growths of skin cells with varying degrees of malignancy.
- Cancers of the epidermis exhibit varying degrees of malignancy.
- Sometimes small blood vessels can be seen within the tumor.
- Crusting and bleeding in the center of the tumor frequently develops.
- Warning signs of malignant melanoma include change in the size, shape, color, or elevation of a mole.