lymphoma

(noun)

A malignant tumor that arises in the lymph nodes or in other lymphoid tissue.

Related Terms

Examples of lymphoma in the following topics:

  • Lymphomas

    • Lymphoma is cancer of the lymphocytes and and is treated with chemotherapy or radiotherapy.
    • Typically, lymphoma is present as a solid tumor of lymphoid cells.
    • Thomas Hodgkin published the first description of lymphoma in 1832, specifically of the form named after him, Hodgkin's lymphoma.
    • The category of non-Hodgkin lymphoma (NHL) is divided into 16 different diseases.
    • Upon histological examination, the node contained follicular lymphoma.

  • Burkitt's Lymphoma

    • Burkitt's lymphoma is a very fast growing form of non-Hodgkin's lymphoma, a cancer in the lymphatic system.
    • Burkitt's lymphoma is a form of non-Hodgkin's lymphoma, a cancer of the lymphatic system (in particular, B lymphocytes).
    • Burkitt's lymphoma involves B-cells and is a rapidly growing cancer.
    • Currently Burkitt's lymphoma can be divided into three main clinical variants:
    • The tumor cells have a similar appearance to that of endemic Burkitt lymphoma.

  • RNA Oncogenic Viruses

    • Kaposi's sarcoma-associated herpesvirus (HHV-8) has been linked to Kaposi's sarcoma and primary effusion lymphoma.
    • Epstein-Barr virus (EBV) has been linked to Burkitt's lymphoma, Hodgkin's lymphoma, post-transplantation lymphoproliferative disease, and nasopharyngeal carcinoma.

  • Spinal Cord Compression

    • Tumors that commonly cause cord compression are lung cancer (non-small cell type), breast cancer, prostate cancer, renal cell carcinoma, thyroid cancer, lymphoma, and multiple myeloma.
    • Some tumors are highly sensitive to chemotherapy (e.g. lymphomas, small-cell lung cancer) and may be treated with chemotherapy alone.

  • Cryptococcosis

    • Other conditions which pose an increased risk include certain lymphomas (e.g.
    • Hodgkin's lymphoma), sarcoidosis, liver cirrhosis, and patients on long-term corticosteroid therapy.

  • Altered Gene Expression in Cancer

    • Myc is a transcription factor that is aberrantly activated in Burkett's Lymphoma, a cancer of the lymph system.
    • Patients with Burkett's lymphoma can develop tumors on their jaw or in their mouth that interfere with the ability to eat.

  • Other Diseases and Epstein-Barr Virus

    • It is also associated with particular forms of cancer, such as Hodgkin's lymphoma, Burkitt's lymphoma, nasopharyngeal carcinoma, and central nervous system lymphomas associated with HIV.

  • DNA Oncogenic Viruses

    • The Epstein-Barr virus has been linked to Burkitt's lymphoma.

  • Ruptured Spleen

    • The spleen is enlarged in a variety of conditions such as malaria, mononucleosis, and, most commonly, in cancers of the lymphatics, such as lymphomas or leukemia.

  • Immunotherapy for Cancer

    • Radioimmunotherapy in turn involves the use of radioactively conjugated murine antibodies against cellular antigens, mostly for treatment of lymphomas.
    • Topical immunotherapy utilizes an immune enhancement cream (imiquimod), which is an interferon producer, causing the patient's own killer T cells to destroy warts, actinic keratoses, basal cell carcinoma, squamous cell carcinoma, cutaneous T cell lymphoma, and superficial spreading melanoma.