hypophyseal portal system
(noun)
The system of blood vessels that link the hypothalamus and the anterior pituitary in the brain.
Examples of hypophyseal portal system in the following topics:
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Hypothalamic-Pituitary Axis
- The collection of these glands makes up the endocrine system.
- The hypothalamus in vertebrates integrates the endocrine and nervous systems.
- This capillary network is a part of the hypophyseal portal system which carries substances from the hypothalamus to the anterior pituitary and hormones from the anterior pituitary into the circulatory system.
- A portal system carries blood from one capillary network to another; therefore, the hypophyseal portal system allows hormones produced by the hypothalamus to be carried directly to the anterior pituitary without first entering the circulatory system.
- The regulatory hormones travel from the hypothalamus through the hypophyseal portal system to the anterior pituitary where they exert their effect.
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Hypothalamus
- The hypothalamus serves as a gateway between the nervous system and endocrine system.
- One of the most important functions of the hypothalamus is linking the nervous system to the endocrine system via the pituitary gland (hypophysis).
- These hormones are released into the bloodstream and target other organ systems, most notably the pituitary.
- The hypothalamus affects the endocrine system and governs emotional behavior such as anger and sexual activity.
- Most of the hypothalamic hormones generated are distributed to the pituitary via the hypophyseal portal system.
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Blood Supply to the Liver
- In the hepatic portal system, the liver receives a dual blood supply from the hepatic portal vein and hepatic arteries.
- In the hepatic portal system, the liver receives a dual blood supply from the hepatic portal vein and hepatic arteries.
- A portal system is a venous structure that enables blood from one set of capillary beds to drain into another set of capillary beds, without first returning this blood to the heart.
- The majority of capillaries in the body drain directly into the heart, making portal systems unusual.
- The hepatic portal system connects the capillaries of the gastrointestinal tract with the capillaries in the liver .
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Hepatic Portal Circulation
- The hepatic portal system is responsible for directing blood from parts of the gastrointestinal tract to the liver.
- The hepatic portal system is the system of veins comprising the hepatic portal vein and its tributaries.
- It functions to supply the liver with metabolites and ensures that ingested substances are processed in the liver before reaching the systemic circulation, limiting the damage ingested toxins may cause.
- The hepatic portal vein supplies about 75% of the blood the liver requires, with the other 25% supplied by the hepatic artery.
- Blood from the hepatic artery is oxygenated but nutrient-poor compared to that supplied by the hepatic portal vein.
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The Posterior Pituitary
- The posterior pituitary (or neurohypophysis) comprises the posterior lobe of the pituitary gland and is part of the endocrine system.
- These axons release peptide hormones into the capillaries of the hypophyseal circulation.
- These are then stored in neurosecretory vesicles (Herring bodies) before being secreted by the posterior pituitary into the systemic bloodstream.
- The infundibular stalk, also known as the infundibulum or pituitary stalk, bridges the hypothalamic and hypophyseal systems.
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Transport of Hormones
- The endocrine system is a system of ductless glands that secrete hormones directly into the circulatory system to be carried long distances to other target organs that regulate key body and organ functions.
- Some endocrine glands secrete into a portal system rather than the systemic circulation that allows for the direct targeting of hormones.
- For example, hormones secreted by the pancreas pass into the hepatic portal vein that transports them directly to the liver.
- Once within the circulatory system a small proportion of hormones circulate freely, however the majority are bound with a transport protein.
- Describe the way in which hormones are transported in the endocrine system
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Veins
- Although most veins take blood back to the heart, portal veins carry blood between capillary beds.
- Since this is an important function in mammals, damage to the hepatic portal vein can be dangerous.
- Blood clotting in the hepatic portal vein can cause portal hypertension, which results in a decrease of blood fluid to the liver.
- Veins are classified in a number of ways, including superficial vs. deep, pulmonary vs. systemic, and large vs. small:
- Systemic veins - Systemic veins drain the tissues of the body and deliver deoxygenated blood to the heart.
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Principal Veins
- In the circulatory system, veins are blood vessels that carry blood towards the heart.
- Deep veins are often of larger caliber than superficial veins and carry the majority of the blood within the circulatory system.
- The above veins form part of the systemic circulatory system.
- The hepatic portal vein carries blood from the gastrointestinal tract to the liver.
- The portal vein is often described as a false vein because it conducts blood between capillary networks rather than between a capillary network and the heart.
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The Anterior Pituitary
- A major organ of the endocrine system, the anterior pituitary (also called the adenohypophysis) is the glandular, anterior lobe of the pituitary gland.
- Follicle-stimulating hormone is a glycoprotein hormone that targets the gonads and effects the growth of the reproductive system.
- At this site, these neurons can release substances into the small blood vessels that travel directly to the anterior pituitary gland (the hypothalamo-hypophysial portal vessels).
- The anterior pituitary, in yellow, is linked to the hypothalamus by a portal system.
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Post-and-Lintel Construction
- Post-and-lintel architecture is a fundamental structural system in which a horizontal header is supported by two vertical columns.
- It is often found over portals, doors, windows, and fireplaces.
- The post-and-lintel method is a fundamental construction system that can be found in Neolithic, Ancient Greek, and Ancient Egyptian architecture.
- The biggest disadvantage of the post-and-lintel system is the limited amount of weight that it can support.
- There are two main force vectors at work in the post-and-lintel system.