Section 3
Eukaryotic Gene Regulation
Book
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By Boundless
By Boundless
Boundless Biology
Biology
by Boundless
6 concepts
The Promoter and the Transcription Machinery
When transcription factors bind to the promoter region, RNA polymerase is placed in an orientation that allows transcription to begin.
Transcriptional Enhancers and Repressors
Enhancers increase the rate of transcription of genes, while repressors decrease the rate of transcription.
Epigenetic Control: Regulating Access to Genes within the Chromosome
Both the packaging of DNA around histone proteins, as well as chemical modifications to the DNA or proteins, can alter gene expression.
RNA Splicing
RNA splicing allows for the production of multiple protein isoforms from a single gene by removing introns and combining different exons.
The Initiation Complex and Translation Rate
The first step of translation is ribosome assembly, which requires initiation factors.
Regulating Protein Activity and Longevity
A cell can rapidly change the levels of proteins in response to the environment by adding specific chemical groups to alter gene regulation.