Examples of ubiquitin in the following topics:
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- Proteins can be chemically modified with the addition of methyl, phosphate, acetyl, and ubiquitin groups.
- The addition of an ubiquitin group to a protein marks that protein for degradation.
- Ubiquitin acts like a flag indicating that the protein lifespan is complete.
- One way to control gene expression is to alter the longevity of the protein: ubiquitination shortens a protein's lifespan.
- Proteins with ubiquitin tags are marked for degradation within the proteasome.
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- In addition, RNAs can be alternately spliced (cut and pasted to create novel combinations and novel proteins) and many proteins are modified after translation by processes such as proteolytic cleavage, phosphorylation, glycosylation, and ubiquitination.