Concept
Version 13
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The Stress Response
Mechanism of stress and stress response
The hypothalmic-pituitary-adrenal (HPA) axis is an endocrine cascade that mediates several aspects of physiological stress, including responses to acute stressors (i.e., fight-or-flight response) but it also causes chronic stress.
This is a diagram of the mechanism of stress and stress response in the HPA axis. The hypothalamus secretes corticotropin releasing hormone and the anterior pituitary responds by releasing adrenocortictotropic hormone, that causes the adrenal cortex to activate a physical response.
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