primary auditory cortex

Examples of primary auditory cortex in the following topics:

• Sensory Areas

  • Parts of the cortex that receive sensory inputs from the thalamus are called primary sensory areas.
  • The primary somatosensory cortex, located across the central sulcus and behind the primary motor cortex, is configured to generally correspond with the arrangement of nearby motor cells related to specific body parts.
  • The primary auditory cortex is located on the transverse gyri that lie on the back of the superior temporal convolution of the temporal lobes.
  • Neighboring points in the primary visual cortex, for example, correspond to neighboring points in the retina.
  • Similarly, there is a tonotopic map in the primary auditory cortex and a somatotopic map in the primary sensory cortex.

• Cerebral Lobes

  • The cortex is divided into four main lobes: frontal, parietal, occipital, temporal.
  • The precentral gyrus, forming the posterior border of the frontal lobe, contains the primary motor cortex, which controls voluntary movements of specific body parts.
  • Adjacent areas in the superior, posterior, and lateral parts of the temporal lobes are involved in high-level auditory processing.
  • The temporal lobe is involved in primary auditory perception such as hearing and holds the primary auditory cortex.
  • The superior temporal gyrus includes an area where auditory signals from the ear first reach the cerebral cortex and are processed by the primary auditory cortex in the left temporal lobe.

• Thalamus

  • It is generally believed to act as a relay between a variety of subcortical areas and the cerebral cortex.
  • For the visual system, for example, inputs from the retina are sent to the lateral geniculate nucleus of the thalamus, which in turn projects to the primary visual cortex in the occipital lobe.
  • Each of the primary sensory relay areas receives strong back projections from the cerebral cortex.
  • Similarly, the medial geniculate nucleus acts as a key auditory relay between the inferior colliculus of the midbrain and the primary auditory cortex.
  • The ventral posterior nucleus is a key somatosensory relay, which sends touch and proprioceptive information to the primary somatosensory cortex.

• Motor Areas

  • The motor areas of the brain are located in both hemispheres of the cortex.
  • Primary motor cortex: Main contributor to the generation of neural impulses that control the execution of movement.
  • Premotor cortex: Located anterior to the primary motor cortex and responsible for some aspects of motor control.
  • It is located on the midline surface of the hemisphere anterior to the primary motor cortex.
  • $$Topography of the human motor cortex, including the premotor cortex, SMA, primary motor cortex, primary somatosensory cortex, and posterior parietal cortex.

• Parts of the Cerebellum

  • Like the cerebral cortex, the cerebellum is divided into two hemispheres.
  • Based on surface appearance, three lobes can be distinguished in the cerebellum: the flocculonodular lobe, anterior lobe (above the primary fissure), and the posterior lobe (below the primary fissure).
  • Its primary connections are with the vestibular nuclei, although it also receives visual and other sensory input.
  • It receives proprioception input from the dorsal columns of the spinal cord (including the spinocerebellar tract) and from the trigeminal nerve, as well as from visual and auditory systems.
  • It receives input exclusively from the cerebral cortex (especially the parietal lobe) via the pontine nuclei (forming corticopontocerebellar pathways), and sends output mainly to the ventrolateral thalamus (in turn connected to motor areas of the premotor cortex and primary motor area of the cerebral cortex) and to the red nucleus.

• Neural Mechanisms (Cortex)

  • The primary motor cortex is the neural center for voluntary respiratory control.
  • The center for diaphragm control is posterior to the location of thoracic control (within the superior portion of the primary motor cortex).
  • The inferior portion of the primary motor cortex may be involved in controlled exhalation.
  • Topography of the primary motor cortex, on an outline drawing of the human brain.
  • Each part of the primary motor cortex controls a different part of the body.

• Cholinergic Neurons and Receptors

  • In the cerebral cortex, tonic ACh inhibits layer 4 neurons, the main targets of thalamocortical inputs while exciting pyramidal cells in layers 2/3 and 5.
  • At the same time, acetylcholine acts through nicotinic receptors to excite certain groups of inhibitory interneurons in the cortex, which further dampen cortical activity.
  • One well-supported function of ACh in the cortex is increased responsiveness to sensory stimuli, a form of attention.
  • Phasic increases of ACh during visual, auditory, and somatosensory stimulus presentations have been found to increase the firing rate of neurons in the corresponding primary sensory cortices.

• Aphasia

  • Individuals with expressive aphasia (also called Broca's aphasia) have lesions to the medial insular cortex.
  • Auditory comprehension is usually preserved.
  • Primary progressive aphasia (PPA) is associated with progressive illnesses or dementia, and is the gradual process of losing the ability to think.
  • They have poor auditory and reading comprehension and fluent, but nonsensical, oral and written expression.
  • The primary goal is to help the individual and those closest to them adjust to changes and limitations in communication.

• Midbrain

  • The midbrain is located below the cerebral cortex and above the hindbrain placing it near the center of the brain.
  • The superior colliculus regulates preliminary visual processing and eye movement, while the inferior colliculus is involved in auditory processing.

• Mapping the Primary Somatosensory Area

  • A cortical homunculus is a pictorial representation of the anatomical divisions of the primary motor cortex and the primary somatosensory cortex; it is the portion of the human brain directly responsible for the movement and exchange of sensory and motor information of the body.
  • The primary somesthetic cortex (sensory) pertains to the signals within the postcentral gyrus coming from the thalamus, and the primary motor cortex pertains to signals within the precentral gyrus coming from the premotor area of the frontal lobes.
  • Typically, the area of the body corresponds to a point on the primary somatosensory cortex (postcentral gyrus).
  • The idea of the cortical homunculus was created by Wilder Penfield and serves as a rough map of the receptive fields for regions of primary somatosensory cortex.
  • The postcentral gyrus is located in the parietal lobe of the human cortex and is the primary somatosensory region of the human brain.