Examples of phospholipids in the following topics:
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- Vitamin K, calcium, and phospholipids are necessary cofactors for proper coagulation, and those deficient in these substances will be more susceptible to uncontrolled bleeding.
- Those with vitamin K deficiency have been shown to produce alternative proteins that improperly bind with phospholipids, which also contributes to the lack of coagulant function.
- Calcium and phospholipids (a platelet membrane constituent) are
required cofactors prothrombin activation enzyme complexes to function.
- Calcium mediates the binding of the tenase enzyme complexes (via the terminal
gamma-carboxy residues on FXa and FIXa) to the phospholipid surfaces
expressed by platelets, which in turn activates prothrombin to produce thrombin, which then produces fibrin from fibrinogen.
- Phosopholipid deficiency is also associated with thrombocytopenia (platelet deficiency) because the phospholipids involved with clotting come from platelets.
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- Lipid- and phospholipid-derived hormones are produced from lipids such as linoleic acid and arachidonic acid.
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- Chylomicrons are lipoprotein particles that consist of triglycerides (85-92%), phospholipids (6-12%), cholesterol (1-3%) and proteins (1-2%).
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- Hepatocytes are involved in protein synthesis, protein storage, transformation of carbohydrates, synthesis of cholesterol, bile salts and phospholipids, and detoxification, modification, and excretion of exogenous and endogenous substances.
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- 4. eicosanoids: hormones containing lipids synthesized from the fatty acid chains of phospholipids found in the plasma membrane.
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- Most of the fats found in food are triglycerides, cholesterol, and phospholipids.
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- Phospholipids and cholesterol, being amphipathic, are transported in the surface monolayer of the lipoprotein particle.
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- In addition, phosphate is found in phospholipids, such as those that make up the cell membrane, and in ATP, nucleotides, and buffers.