Examples of phosphocreatine in the following topics:
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- Creatine supplements may increase anaerobic exercise performance by augmenting phosphocreatine levels and ATP availability.
- Supplements of creatine can reduce or mitigate these negative effects of exercise, primarily by increasing the availability of phosphocreatine to muscles.
- This is a reflection of the differential energy pools used for anaerobic versus aerobic respiration, specifically the prioritization of use of phosphocreatine as an ATP pool for Type II muscles, which are primarily used during anaerobic exercise.
- Phosphocreatine is an important source of energy-rich phosphate groups that can be added to available ADP to resynthesize ATP for muscle contractions.
- Molecular structure of phosphocreatine donates the high energy phosphate group to ADP and acts as a short-term energy pool for muscle contractions.
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- Phosphocreatine, also known as creatine phosphate, can rapidly donate a phosphate group to ADP to form ATP and creatine under anaerobic conditions.
- Enough phosphocreatine is present in the muscle to provide ATP for up to 15 seconds of contraction.
- The reaction of phosphocreatine + ADP to ATP + creatine is reversible.
- During periods of rest, the store of phosphocreatine is regenerated from ATP.
- Cellular respiration plays a key role in returning the muscles to normal after exercise, converting the excess pyruvate into ATP and regenerating the stores of ATP, phosphocreatine, and glycogen in the muscle that are required for more rapid contractions.