occludin

(noun)

A protein forming the main component of the tight junctions, along with the claudin group of proteins.

Related Terms

Examples of occludin in the following topics:

  • Tight Junctions

    • The occludins and claudins are the major components of tight junction strands.
    • Model of the protein structure of the coiled-coil domain of human occludin.

  • Blood-Brain Barrier

    • At the interface between blood and the brain, endothelial cells are joined by these tight junctions, which are composed of smaller subunits, frequently biochemical dimers that are transmembrane proteins such as occludin, claudins, and junctional adhesion molecule.