LH

(noun)

Luteinizing hormone is produced by the anterior pituitary gland and in males causes the synthesis and secretion of testosterone and androgen.

Related Terms

Examples of LH in the following topics:

  • Hormonal Regulation of the Female Reproductive Cycle

    • LH induces androgen synthesis by theca cells, stimulates proliferation and differentiation, and increases LH receptor expression on granulosa cells.
    • Estrogen levels are highest right before the LH surge begins.
    • Ovulation normally occurs 30 (± 2) hours after the beginning of the LH surge.
    • Ovulation is triggered by a spike in the amount of FSH and LH released from the pituitary gland.
    • Human chorionic gonadotropin is structurally similar to LH and can preserve the corpus luteum.

  • Ovarian Cycle

    • Many endocrinologists believe that estrogen secretion of the dominant follicle increases to a level that indirectly lowers the levels of LH and FSH.
    • Ovulation normally occurs 30 (± 2) hours after the beginning of the LH surge (when LH is first detectable in urine).
    • After ovulation, the pituitary hormones FSH and LH cause the remaining parts of the dominant follicle to transform into the corpus luteum.
    • The hormones produced by the corpus luteum suppress production of the FSH and LH, causing the corpus luteum will atrophy.
    • After implantation, human embryos produce human chorionic gonadotropin (hCG), which is structurally similar to LH and can preserve the corpus luteum.

  • Hormonal Regulation of the Male Reproductive System

    • Studies from rodent models suggest that gonadotropin hormones (both LH and FSH) support the process of spermatogenesis by suppressing the proapoptotic signals and thus promoting spermatogenic cell survival.
    • There it stimulates the synthesis and secretion of the gonadotropins, FSH and luteinizing hormone (LH).
    • Luteinizing hormone (LH) is released by the anterior pituitary gland.
    • In the testes, LH binds to receptors on Leydig cells, which stimulates the synthesis and secretion of testosterone.

  • Hormonal Methods

    • Progesterone negative feedback decreases the frequency of gonadotropin-releasing hormone (GnRH) released by the hypothalamus, which decreases the release of follicle-stimulating hormone (FSH), and greatly decreases the release of luteinizing hormone (LH) by the anterior pituitary.
    • Progesterone negative feedback and the lack of estrogen positive feedback on LH release, prevent a mid-cycle LH surge.
    • Inhibition of follicular development and the absence of a LH surge prevent ovulation.

  • Puberty

    • GnRH signals from the hypothalamus induce pulsed secretion of LH (and to a lesser degree, FSH) at roughly one to two hour intervals.
    • LH stimulates the Leydig cells of the testes to make testosterone and blood levels begin to rise.
    • For females, as the amplitude of LH pulses increases, the theca cells of the ovaries begin to produce testosterone and smaller amounts of progesterone.
    • Hormones include: 1 Follicle-stimulating hormone - FSH. 2 Luteinizing hormone - LH. 3 Progesterone. 4 Estrogen. 5 Hypothalamus. 6 Pituitary gland. 7 Ovary. 8 Pregnancy - hCG (Human chorionic gonadotropin). 9 Testosterone. 10 Testicle. 11 Incentives. 12 Prolactin - PRL.

  • Pituitary Gland Disorders

    • In response to the releasing hormone rate, the anterior pituitary produces its hormones (TSH, ACTH, LH, FSH, GH) that stimulate effector hormone glands in the body, although prolactin acts directly on the breast gland.
    • Measurement of ACTH and growth hormone usually requires dynamic testing, whereas the other hormones (LH/FSH, prolactin, TSH) can typically be tested with basal levels.

  • Ovaries

    • When oocyte maturation is completed, a luteinizing hormone (LH) surge secreted by the pituitary gland stimulates follicle rupture and oocyte release.