Examples of autoimmune diseases in the following topics:
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- Autoimmune diseases are an inappropriate immune response against tissues in the body.
- Autoimmune diseases are commonly considered complex immune disorders.
- While many autoimmune diseases are rare, collectively these diseases afflict millions of patients.
- However, defects of one or more of these genes do not cause an autoimmune disease, but only predispose a person for an autoimmune disease.
- The factors that trigger an autoimmune disease are still unknown.
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- Systemic lupus erythematosus (SLE) is an autoimmune disease that can occur in any organ or tissue in the body.
- Systemic lupus erythematosus, often abbreviated to SLE or lupus, is a systemic autoimmune disease (or autoimmune connective tissue disease) that can affect any part of the body.
- As with other autoimmune diseases, the immune system attacks the body's own cells and tissue, resulting in inflammation and tissue damage.
- The course of the disease is unpredictable, with periods of illness (called flares) alternating with remissions.
- It is the prototypical autoimmune disease.
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- Ankylosing spondylitis is a chronic inflammatory, autoimmune disease that results in joint fusion in the vertebrae and the sacroiliac joint.
- AS is a form of spondyloarthritis, a chronic, inflammatory arthritis and autoimmune disease.
- However, only 5% of individuals with the HLA-B27 genotype contract the disease
- Symptoms of the disease first appear, on average, at age 23 years.
- Men are affected more than women by a ratio of about 3:1, with the disease usually taking a more severe course in men than women.
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- Psoriasis is an autoimmune disease that affects the skin, caused by faulty immune signals that speed up the growth cycle of skin cells.
- Psoriasis is an autoimmune disease that affects the skin.
- Typically, topical agents are used for mild disease, phototherapy for moderate disease, and systemic immunosuppressant agents for severe disease.
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- Addison's disease and congenital adrenal hyperplasia can manifest as adrenal insufficiency.
- One subtype is called idiopathic or unknown cause of adrenal insufficiency. 80% are due to an autoimmune disease called Addison's disease or autoimmune adrenalitis.
- Tertiary adrenal insufficiency is due to hypothalamic disease and decrease in corticotropin releasing factor (CRF).
- For chronic adrenal insufficiency, the major contributors are autoimmune adrenalitis, tuberculosis, AIDS, and metastatic disease.
- Autoimmune adrenalitis may be part of Type 2 autoimmune polyglandular syndrome, (which can include type 1 diabetes), hyperthyroidism, autoimmune thyroid disease (also known as autoimmune thyroiditis and Hashimoto's disease).
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- Sjögren's syndrome is an autoimmune disease in which immune cells attack and destroy the exocrine glands that produce tears and saliva.
- Sjögren's syndrome, also known as "Mikulicz disease" and "Sicca syndrome," is a systemic autoimmune disease in which immune cells attack and destroy the exocrine glands that produce tears and saliva.
- It is estimated to affect as many as 4 million people in the United States alone, making it the second most common autoimmune rheumatic disease.
- Sjögren's can damage vital organs of the body, and its symptom may plateau, worsen, or go into remission, as with other autoimmune diseases.
- Some people may experience only the mild symptoms of dry eyes and mouth, while others have symptoms of severe disease.
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- Systemic lupus erythematosus is an autoimmune disease that can affect any part of the body, leading to inflammation and tissue damage.
- Systemic lupus erythematosus, often abbreviated to SLE or lupus, is a systemic autoimmune disease (or autoimmune connective tissue disease) that can affect any part of the body.
- As occurs in other autoimmune diseases, the immune system attacks the body's cells and tissue, resulting in inflammation and tissue damage.
- Mild or remittent disease may, sometimes, be safely left untreated.
- Drugs unrelated to SLE should be prescribed only when known not to exacerbate the disease.
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- The cause is unknown, but it may result from either a viral infection or an autoimmune reaction.
- In the latter case, it is a systemic autoimmune disease.
- Some cases of dermatomyositis actually "overlap" (i.e., coexist with or are part of a spectrum that includes) other autoimmune diseases such as Sjögren's syndrome, lupus, scleroderma, or vasculitis.
- Polymyositis is also associated with interstitial lung diseases.
- The cause of polymyositis is unknown and may involve viruses and autoimmune factors.
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- This process does not remove thymocytes that may become sensitized against self-antigens, which causes autoimmunity.
- The potentially autoimmune cells are removed by the process of negative selection.
- This process is an important component of central tolerance, or the ability for immune cells to not attack parts of the "self", and serves to prevent the formation of self-reactive T cells that are capable of inducing autoimmune diseases in the host.
- Autoimmune diseases reflect a loss of central tolerance, in which the body's own B and T cells become sensitized towards self antigens.
- Many autoimmune disorders are humoral in that they are primarily antibody mediated, but many disorders are T cell mediated instead, such as Chrohn's disease (a disease in which T cells attack the colon).
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- A hypersensitivity reaction refers to an overreactive immune system triggered by allergies and autoimmunity.
- Hypersensitivity (also called hypersensitivity reaction) refers to undesirable reactions produced by the normal immune system, including allergies and autoimmunity, and are commonly mediated by antibodies.
- Associated disorders: Autoimmune hemolytic anemia, thrombocytopenia, Erythroblastosis, fetalis, Goodpasture's syndrome, Membranous nephropathy, Graves' disease, Myasthenia Gravis.
- Associated disorders: Contact dermatitis, Mantoux test, Chronic transplant rejection, Multiple sclerosis, T-cells VAutoimmune disease receptor mediated, Graves' disease,Myasthenia Gravis.