Examples of uncoating in the following topics:
-
- Another drug target is the uncoating step during viral infection.
- Uncoating is the process of capsid disintegration, which leads to the release of the genomic material.
- It is believed that such drugs prevent the virus from uncoating by blocking the proteins on the capsid responsible for uncoating, such as ion channel proteins.
-
- It may interfere with virion binding to receptors, block uptake into cells, prevent uncoating of the genomes in endosomes, or cause aggregation of virus particles.
-
- There are six basic stages in the life cycle of viruses: attachment, penetration, uncoating, replication, assembly of viral particles, and release.
-
- Once inside a cell, all viruses must uncoat, replicate, and transcribe their genomes, and then repackage their genomes into viral progeny that are released from cells.
-
- Uncoating of the viral RNA is mediated by receptor-dependent destabilization of the virus capsid (2).
-
- Uncoating is a process in which the viral capsid is removed: This may be by degradation by viral or host enzymes or by simple dissociation.
-
- Prior to genome replication, the processes of viral attachment, entry and uncoating occur.