serology

Examples of serology in the following topics:

• Serology

  • Serology is the study of blood serum and other bodily fluids for the identification of antibodies.
  • Serology is the scientific study of blood serum and other bodily fluids.
  • In practical immunological terms, serology is the diagnostic identification of antibodies in the serum.
  • Serological tests are performed on blood serum, and body fluids such as semen and saliva.
  • Describe how serology can be used to identify antibodies in blood serum and other bodily fluids

• Precipitation Reactions

  • Precipitation reactions are serological assays for the detection of immunoglobulin levels from the serum of a patient with infection.
  • Precipitation reactions are less sensitive than agglutination reactions but remain gold standard serological techniques.
  • The most commonly used serologic precipitation reactions are the Ouchterlony test (based on double immunodiffusion and named after the Swedish physician who invented it), and the Mancini method (based on single radial immunodiffusion).

• Genital Ulcer Diseases

  • ., testing is recommended for syphilis (by serology and darkfield microscopy) and HSV (culture, serology or PCR), and in cases of chancroid outbreaks or based on the medical history, for the presence of Haemophilus ducreyi.

• Specimen Collection

  • Serum is the preferred specimen source for serologic testing.
  • Refrigerated CSF is acceptable for a limited number of serologic tests; however, if PCR is to be performed for the viral panels, the specimen must be frozen and shipped on dry ice.

• Chikungunya Fever

  • Common laboratory tests for chikungunya include RT-PCR, virus isolation, and serological tests.
  • Serological diagnosis requires a larger amount of blood than the other methods, and uses an ELISA assay to measure chikungunya-specific IgM levels.

• Cultivation of Specimen

  • Serological testing uses in-vitro diagnostic testing of serum, has a high degree of specificity and sensitivity, and is based on the specificity an antibody has for its antigen.

• Lymphogranuloma Venereum

  • Diagnosis is made after serological analysis and exclusion of other reasons for genital ulcers and lymphatic issues.

• Immunoassays for Disease

  • These biochemical and serological techniques are based on the detection and quantitation of antibodies generated against an infectious agent, a microbe, or non-microbial antigen.

• Chancroid (Soft Chancre)

  • Even though serological and genetic tests can be used for identification, they are not widely used and culturing is the main tool for identifying Haemophilus ducreyi.

• Arboviral Encephalitis

  • TBE and other arboviral encephalitis can be diagnosed through a combination of blood tests, particularly immunologic, serologic, and/or virologic techniques such as ELISA, complement fixation, polymerase chain reaction, Neutralization test, and Hemoagglutination Inhibition test.