lysozyme
(noun)
A bacteriolytic (or antibiotic) enzyme found in many animal secretions and in egg white.
Examples of lysozyme in the following topics:
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Normal Eye Microbiota
- Tears contain bactericides such as lysozyme, so that microorganisms have difficulty in surviving the lysozyme and settling on the epithelial surfaces.
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Peptidoglycan Synthesis and Cell Division
- That is why the cell wall of Archaea is insensitive to lysozyme.
- That is why the cell wall of Archaea is insensitive to lysozymes, which are present in human sweat and tears as part of innate immunity.
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Innate Resistance
- Enzymes such as lysozyme and phospholipase A2 in saliva, tears, and breast milk are also antibacterials.
- Tears contain bactericides such as lysozyme, so that microorganisms have difficulty in surviving the lysozyme and settling on the epithelial surfaces.
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Macrophages
- Macrophages can be identified by specific expression of a number of proteins including CD14, CD40, CD11b, F4/80(mice)/EMR1(human), lysozyme M, MAC-1/MAC-3 and CD68.
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Diverse Cell Forms of Methanogens
- These differences makes these archaea resistant to the enzyme, lysozyme, which only breaks down β (1,4) sugar linkages like those found in peptidoglycan.
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Natural Passive Immunity
- In addition to the IgA and IgG, human milk also contains: oligosaccharides and mucins that adhere to bacteria and viruses to interfere with their attachment to host cells; lactoferrin to bind iron and make it unavailable to most bacteria; B12 binding protein to deprive bacteria of needed vitamin B12; bifidus factor that promotes the growth of Lactobacillus bifidus, normal flora in the gastrointestinal tract of infants that crowds out harmful bacteria; fibronectin that increases the antimicrobial activity of macrophages and helps repair tissue damage from infection in the gastrointestinal tract; gamma-interferon, a cytokine that enhances the activity of certain immune cells; hormones and growth factors that stimulate the baby's gastrointestinal tract to mature faster and be less susceptible to infection; and lysozyme to break down peptidoglycan in bacterial cell walls.
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Phage Display
- The new phages produce lysozyme that ruptures the cell wall of the host, leading to the release of the new phages, each ready to invade other bacterial cells.
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Virulent Bacteriophages and T4
- The lysozyme domain of GP5 is activated and degrades the periplasmic peptidoglycan layer.
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Firmicutes
- The spore is sometimes surrounded by a thin covering known as the exosporium, which overlies the spore coat, which acts like a sieve that excludes large toxic molecules like lysozyme, is resistant to many toxic molecules and may also contain enzymes that are involved in germination.