integrin

(noun)

Any of many heterodimeric transmembrane proteins that function as receptors in communication between cells.

Related Terms

Examples of integrin in the following topics:

  • HIV Attachment and Host Cell Entry

    • The HIV coat protein, gp120, binds to integrin α4β7, activating LFA-1 (the central integrin involved in the establishment of bridges known as "virological synapses") which facilitate efficient cell-to-cell spreading of HIV-1.

  • Planctomycetes

    • One such example is a gene sequence (in Gemmata obscuriglobus) that was found to have significant homology to the integrin alpha-V, a protein that is important in transmembrane signal transduction in eukaryotes.

  • Double-Stranded DNA Viruses: Adenoviruses

    • Next, a specialized motif in the penton base protein interacts with αv integrin, stimulating internalization of the adenovirus via clathrin-coated pits, resulting in entry of the virion into the host cell within an endosome.