agglutination
(noun)
the clumping together of red blood cells or bacteria, usually in response to a particular antibody
Examples of agglutination in the following topics:
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Agglutination Reactions
- Agglutination is the visible expression of the aggregation of antigens and antibodies.
- Agglutination reactions apply to particulate test antigens that have been conjugated to a carrier.
- Various methods of agglutination are used in diagnostic immunology and these incude latex agglutination, flocculation tests, direct bacterial agglutination, and hemagglutination.
- Direct bacterial agglutination uses whole pathogens as a source of antigen.
- Describe how agglutination reactions can be used to assess the presence of antibodies in a specimen
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Precipitation Reactions
- Precipitation reactions differ from agglutination reactions in the size and solubility of the antigen and sensitivity.
- Precipitation reactions are less sensitive than agglutination reactions but remain gold standard serological techniques.
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Cultivation of Specimen
- Serum can be directly used in agglutination, precipitation, complement fixation, fluorescent microscopy, and enzyme-linked assays.