synapsis
(noun)
the association of homologous maternal and paternal chromosomes during the initial part of meiosis
Examples of synapsis in the following topics:
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Meiosis I
- The tight pairing of the homologous chromosomes is called synapsis.
- In synapsis, the genes on the chromatids of the homologous chromosomes are aligned with each other.
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Chromosomal Structural Rearrangements
- To maintain point-for-point synapsis during meiosis, one homolog must form a loop, and the other homolog must mold around it.
- Although this topology can ensure that the genes are correctly aligned, it also forces the homologs to stretch and can be associated with regions of imprecise synapsis.
- When one chromosome undergoes an inversion, but the other does not, one chromosome must form an inverted loop to retain point-for-point interaction during synapsis.
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Disorders in Chromosome Number
- Misaligned or incomplete synapsis, or a dysfunction of the spindle apparatus that facilitates chromosome migration, can cause nondisjunction.
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Gene rearrangement within genomes
- It is known that this pairing and interaction between homologous chromosomes, known as synapsis, does more than simply organize the homologs for migration to separate daughter cells.
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Forms of Signaling
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Genetic Linkage and Distances
- It is now known that the pairing and interaction between homologous chromosomes, known as synapsis, does more than simply organize the homologs for migration to separate daughter cells.
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Generalized Recombination and RecA