sensitization

Examples of sensitization in the following topics:

• Sensitivity Analysis

  • Sensitivity analysis determines how much a change in an input will affect the output.
  • Sensitivity analysis is a statistical tool that determines how consequential deviations from the expected value occur.
  • This helps us in determining the sensitivity of the data we supply for the problem.
  • Sensitivity analysis can be useful for a number of reasons, including:
  • The sensitivity analysis entails changing each variable and seeing how that changes the output .

• The Interest Rate Risk

  • On the other hand, the fixed-rate assets and liabilities are not sensitive to interest rate changes.
  • If the interest-rate sensitive liabilities exceed the interest-rate sensitive assets, then rising interest rates cause banks' profits to plummet, while falling interest rates cause banks' profits to increase.
  • If the interest-rate sensitive liabilities equal the interest-rate sensitive assets, then fluctuating interest rates do not affect bank profits.
  • For example, if the bank manager knows the interest-rate sensitive liabilities exceed the interest-rate sensitive assets, and he believes interest rates will fall, then he will do nothing.
  • If a bank manager thinks interest rates will increase, subsequently, he would boost interest-rate sensitive assets and decrease interest-rate sensitive liabilities by manipulating balance sheet items.

• Employ Empathy and Sensitivity

  • Appeals to empathy and sensitivity can be exceedingly effective, but only if used correctly.
  • Appealing to the empathy and sensitivity of the audience is broadly termed an emotional appeal.
  • Appeals to empathy and sensitivity can create a sense of connection and trust between you and the audience.

• Status-Quo Pricing of Existing Products

  • Price-Quality Effect: Buyers are less sensitive to price the more higher prices signal higher quality.
  • The first, derived demand, referes to buying sensitivity relative to the price of the end benefit; the more sensitive they will be to the prices of those products that contribute to that benefit.
  • The smaller the given components share of the total cost of the end benefit, the less sensitive buyers will be to the component's price.
  • The Framing Effect: Buyers are more price sensitive when they perceive the price as a loss rather than a forgone gain, and they have greater price sensitivity when the price is paid separately rather than as part of a bundle.
  • Compare Nagle and Holden's nine laws of price sensitivity with status-quo pricing

• Organizational Objectives

  • Price-quality effect – Buyers are less sensitive to price the more that higher prices signal higher quality.
  • Derived demand: The more sensitive buyers are to the price of the end benefit, the more sensitive they will be to the prices of those products that contribute to that benefit.
  • The smaller the given component's share of the total cost of the end benefit, the less sensitive buyers will be to the component's price.
  • Shared-cost effect – The smaller the portion of the purchase price buyers must pay for themselves, the less price sensitive they will be.
  • The framing effect – Buyers are more price sensitive when they perceive the price as a loss rather than a forgone gain, and they have greater price sensitivity when the price is paid separately rather than as part of a bundle.

• Color Vision

  • The sensitivity to luminance drops off at low spatial frequencies, showing that we are not very good at estimating absolute luminance levels as long as they do not change with time - the luminance sensitivity to temporal fluctuations (flicker) does not fall off at low spatial frequencies.
  • The maximum chrominance sensitivity is much lower than the maximum luminance sensitivity with blue-yellow (U) sensitivity being about half of red-green (V) sensitivity and about 16 of the maximum luminance sensitivity.
  • The chrominance sensitivities fall off above 1 cycle / degree, requiring a much lower spatial bandwidth than luminance.
  • The U and V components may be sampled at a lower rate than Y (due to narrower bandwidth) and may be quantified more coarsely (due to lower contrast sensitivity).
  • This graph shows the sensitivity of the eye to luminance (Y) and chrominance (U, V) components of images.

• Sensitivity to Human Relations

  • Good managers have an innate sensitivity to the needs of the people they manage, and a highly developed emotional intelligence.
  • As a result, managers who are sensitive to human resources are much more likely to be successful in a leadership role.
  • The skills required to lead from a human sensitivity perspective are often referred to as soft skills or EQ (emotional intelligence).
  • High performing managers are sensitive to the needs, emotions, perspectives ,and well-being of the individuals they are managing.
  • With the above core skills in mind, managers with a strong sense of human resource sensitivity focus on managing people via the following four phases:

• Sensory Adaptation

  • Meissner's corpuscles are sensory triggers of physical sensations on the skin, especially areas of the skin that are sensitive to light and touch.
  • When the stimulus is removed, the corpuscles regain their sensitivity.
  • In contrast, sensitization is an increase in behavioral responses following repeated applications of a particular stimulus.
  • Unlike sensory adaptation, in which a large amount of stimulus is needed to incur any further responsive effects, in sensitization less and less stimulation is required to produce a large response.
  • Sensory adaptation and sensitization are thought to form an integral component of human learning and personality.

• Habituation, Sensitization, and Potentiation

  • Potentiation, habituation, and sensitization are three ways in which stimuli in the environment produce changes in the nervous system.
  • Three ways in which this occurs include long-term potentiation, habituation, and sensitization.
  • Sensitization is the strengthening of a neurological response to a stimulus due to the response to a secondary stimulus.
  • Habituation and sensitization work in different ways neurologically.
  • In sensitization, however, there are more pre-synaptic neurotransmitters, and the neuron itself is more excitable.

• Alkene Isomerization

  • Thus, a sensitizer triplet (Zt), generated from sensitizer molecule Zs, reacts with a ground state stilbene molecule (Ms) in the following manner:
  • The first diagram below illustrates important features of this sensitization reaction.
  • A variety of useful sensitizers have been identified in the second diagram below.
  • The unexpected change in steady state isomer distribution with the triplet energy of the sensitizer could not be rationalized as a single classical energy transfer.
  • As the triplet energy of the sensitizer drops below 57 kcal/mole, two changes occur.