leakage channel
(noun)
The simplest type of ion channel, with more or less constant permeability.
Examples of leakage channel in the following topics:
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Ion Channels
- Leakage channels are the simplest type of ion channel, in that their permeability is more or less constant.
- The types of leakage channels with the greatest significance in neurons are potassium and chloride channels.
- There are three main types of gated channels: chemically-gated or ligand-gated channels, voltage-gated channels, and mechanically-gated channels.
- Voltage-gated ion channels, also known as voltage-dependent ion channels, are channels whose permeability is influenced by the membrane potential.
- Ligand-gated ion channels (LGICs) are one type of ionotropic receptor or channel-linked receptor.
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Nerve Impulse Transmission within a Neuron: Resting Potential
- Ion channels have different configurations: open, closed, and inactive .
- Ion channels that change their structure in response to voltage changes are called voltage-gated ion channels.
- The cell possesses potassium and sodium leakage channels that allow the two cations to diffuse down their concentration gradient.
- However, the neurons have far more potassium leakage channels than sodium leakage channels.
- At the peak action potential, K+ channels open and the cell becomes (c) hyperpolarized.
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Nerve Impulse Transmission within a Neuron: Action Potential
- The action potential travels down the neuron as Na+ channels open.
- The Na+ channels close, beginning the neuron's refractory period.
- Eventually, the extra K+ ions diffuse out of the cell through the potassium leakage channels, bringing the cell from its hyperpolarized state back to its resting membrane potential.
- The flow of ions through these channels, particularly the Na+ channels, regenerates the action potential over and over again along the axon.
- Nodes contain voltage-gated K+ and Na+ channels.
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Channel Integration
- The integration of marketing channels to varying degrees is known either as multi-channel or omni-channel retailing.
- The integration of marketing channels involves a process known as multi-channel retailing.
- Omni-channel retailing is very similar to, and an evolution of, multi-channel retailing.
- The omni-channel consumer wants to use all channels simultaneously and retailers using an omni-channel approach will track customers across all channels, not just one or two.
- Merchandise and promotions are not channel specific, but rather consistent across all retail channels.
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Channels for Consumer Goods
- Channels don't always make sense.
- The channel mechanism also operates for service products.
- The channel operates 24 hours a day and exists in an environment where change is the norm.
- Finally, channels should have certain distribution objectives guiding their activities.
- Channels usually represent the largest costs in marketing a product.
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Urinary Incontinence
- Urinary incontinence (UI) is any involuntary leakage of urine.
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Channels for Industrial Goods
- A marketing channel is the network of organizations that work together to provide goods for consumption.
- This definition implies several important characteristics of the channel.
- Yet all must be recognized, selected, and integrated into an efficient channel arrangement.
- The channel operates 24 hours a day and exists in an environment where change is the norm.
- This trade channel is feasible when agents cannot directly sell to industrial users.
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Selecting Marketing Channels
- Channels can range in levels from two to several (five being typical).
- The type of product dictates the number of marketing channels to use.
- Once the number of levels is decided, the channel manager must determine the actual number of channel components involved at each level.
- Regardless of the channel framework selected, channels usually perform better if someone is in charge, providing some level of leadership.
- Given the restrictions inherent in channel leadership, the final question is always "who should lead the channel?
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Channel
- The channel is the method (auditory and visual) that is used to transmit the message to the receiver.
- These cues are received by the listeners through the visual part of the channel: their sense of sight.
- The speaker uses a channel to transmit the message to the audience.
- The channel in the middle links the speaker with the receiver of the message.
- Give examples of auditory and visual channels used in public speaking
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The Significance of Marketing Channels
- A channel performs three important functions.
- Not all channel members perform the same function.
- Second, all channel institutional members are part of many channel transactions at any given point in time.
- A channel strategy is evident.
- Identify the types of institutions that participate in marketing channels, and the three primary functions of these channels