gigantism
Biology
(noun)
a condition caused by an over-production of growth hormone, resulting in excessive bone growth
Physiology
Examples of gigantism in the following topics:
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Hormonal Abnormalities and Height
- This condition of growth hormone excess is rare in children and is referred to as pituitary gigantism because the excessive growth hormone produces excessive growth of bones, and the child can achieve excessive height: from 2.1 to 2.7 m (6'11" to 8'11") in stature by adulthood if left untreated.
- The distinction between gigantism (occurring in children) and acromegaly (occurring in adults) can be made by the occurrence of the adenoma in relation to the closure of the epiphyses.
- If elevated growth hormone levels occur before the closure of the epiphyses (i.e. in prepubertal children), then gigantism ensues.
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Pituitary Gland Disorders
- Growth hormone (GH) excess is rare in children and is referred to as pituitary gigantism , because the excessive growth hormone produces excessive growth of bones and the child can achieve excessive height; from 2.1 to 2.7 m (6'11" to 8'11") in stature by adulthood if left untreated.
- The distinction between gigantism (occurring in children) and acromegaly (occurring in adults) can be made by the occurrence of the adenoma in relation to the closure of the epiphyses.
- If elevated growth hormone levels occur before the closure of the epiphyses (i.e. in prepubertal children), then gigantism ensues.
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Regulation of the Cell Cycle by External Events
- A lack of HGH can inhibit cell division, resulting in dwarfism, whereas too much HGH can result in gigantism .
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Hormonal Regulation of Growth
- Oversecretion of growth hormone can lead to gigantism in children, causing excessive growth.
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The Fossil Record as Evidence for Evolution
- Like extant organisms, fossils vary in size from microscopic, like single-celled bacteria, to gigantic, like dinosaurs and trees.
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Trading blocs and agreements
- Experience in multilingual marketing would help non-European companies succeed in this gigantic market.
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Ending Punctuation
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The Economy Under the Ming Dynasty
- Ming agriculture was much changed from the earlier areas; firstly, gigantic areas, devoting and specializing in cash crops, sprung up to demand from the new market economy.
- Secondly, agricultural tools and carts, some water-powered, help to create a gigantic agricultural surplus which formed the basis of the rural economy.
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The Great Steel Strike
- The union attempted to organize workers in the tin industry, but a sudden wave of industry consolidations left the union facing the gigantic US Steel Corporation.
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Challenges to the New Deal
- Contemporary media dismissed the plot, with a New York Times editorial characterizing it as a "gigantic hoax".