Examples of chylomicrons in the following topics:
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Regulation of Blood Cholesterol Levels
- Chylomicrons, the least dense type of cholesterol transport molecules, contain apolipoprotein B-48, apolipoprotein C, and apolipoprotein E in their shells.
- Chylomicrons are the transporters that carry fats from the intestine to muscle and other tissues that need fatty acids for energy or fat production.
- Cholesterol that is not used by muscles remains in more cholesterol-rich chylomicron remnants, which are taken up from here to the bloodstream by the liver.
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Digestion and Absorption
- These large spheres are called chylomicrons.
- Chylomicrons contain triglycerides, cholesterol, and other lipids; they have proteins on their surface.
- Together, they enable the chylomicron to move in an aqueous environment without exposing the lipids to water.
- Chylomicrons leave the absorptive cells via exocytosis, entering the lymphatic vessels.
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Functions of the Lymphatic System
- During fat digestion, many fatty acids are digested, emulsified, and converted within intestinal cells into a lipoprotein called chylomicrons.
- Lymph drainage vessels that line the intestine are called lacteals, and absorb the chylomicrons into lymph fluid.
- The lymph vessels then take the chylomicrons into blood circulation where they react with HDL cholesterols and are then broken down in the liver.
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Absorptive State
- Chylomicrons are lipoprotein particles that consist of triglycerides (85-92%), phospholipids (6-12%), cholesterol (1-3%) and proteins (1-2%).