β-pleated sheet

(noun)

secondary structure of proteins where N-H groups in the backbone of one fully-extended strand establish hydrogen bonds with C=O groups in the backbone of an adjacent fully-extended strand

Related Terms

Examples of β-pleated sheet in the following topics:

  • Protein Structure

    • In β-pleated sheets, stretches of amino acids are held in an almost fully-extended conformation that "pleats" or zig-zags due to the non-linear nature of single C-C and C-N covalent bonds. β-pleated sheets never occur alone.
    • They have to held in place by other β-pleated sheets.
    • The stretches of amino acids in β-pleated sheets are held in their pleated sheet structure because hydrogen bonds form between the oxygen atom in a polypeptide backbone carbonyl group of one β-pleated sheet and the hydrogen atom in a polypeptide backbone amino group of another β-pleated sheet.
    • The β-pleated sheets which hold each other together align parallel or antiparallel to each other.
    • The R groups of the amino acids in a β-pleated sheet point out perpendicular to the hydrogen bonds holding the β-pleated sheets together, and are not involved in maintaining the β-pleated sheet structure.

  • Facilitated transport

    • Some of these integral proteins are collections of beta-pleated sheets that form a channel through the phospholipid bilayer.